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啄伤导致的不寻常眼眶毛霉病:4 例免疫功能正常的儿科患者的临床特征和结局。

Unusual orbital mucormycosis due to pecking injury: clinical characteristics and outcomes of four immunocompetent pediatric patients.

机构信息

Department of Ophthalmology, Imam Khomeini Hospital, Tehran University of Medical sciences, Tehran, Iran.

Department of Ophthalmology, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Orbit. 2024 Oct;43(5):649-655. doi: 10.1080/01676830.2023.2252054. Epub 2023 Sep 12.

Abstract

Mucormycosis is a serious fungal infection caused by fungi in the order of Mucorales. Orbital mucormycosis occurs more frequently in rhino-orbital, sino-orbital, and rhino-orbito-cerebral forms of the disease, while isolated orbital mucormycosis is much less common. Herein, we present four cases of immunocompetent children who developed primary cutaneous mucormycosis, which subsequently invaded and progressed to orbital mucormycosis following direct traumatic injury caused by pecking from (Common Myna). Given the low prevalence of orbital mucormycosis in healthy children, an unknown source of infection and delayed diagnosis followed by late therapeutic interventions could result in life-threatening conditions and serious sequelae.

摘要

毛霉菌病是一种由毛霉目真菌引起的严重真菌感染。眼眶毛霉菌病多发生于鼻-眶、鼻-颅-眶型,孤立性眼眶毛霉菌病则少见。本文报告了 4 例免疫功能正常的儿童,他们患有原发性皮肤毛霉菌病,随后因啄伤(八哥)引起的直接创伤而感染并进展为眼眶毛霉菌病。由于健康儿童的眼眶毛霉菌病发病率较低,感染源不明且诊断延迟,随后治疗干预较晚,可能导致危及生命的情况和严重的后遗症。

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