Department of Radiology, Turkish Ministry of Health Ankara City Hospital, Ankara, Turkey.
Department of Radiology, Kecioren Training and Research Hospital, Ankara, Turkey .
J Infect Dev Ctries. 2023 Aug 31;17(8):1063-1069. doi: 10.3855/jidc.16698.
Computed tomography (CT) has an important role in the rapid diagnosis, treatment, and management of lower respiratory tract infections. This study aimed to explore different imaging characteristics between Coronavirus disease 2019 (COVID-19) and atypical pneumonia (non-COVID-19) on chest CT of patients admitted to the emergency department.
CT features of 120 patients with positive Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by reverse transcriptase-polymerase chain reaction (RT-PCR) and 83 patients with negative SARS-CoV-2 by RT-PCR but positive respiratory tract sample test results for other respiratory pathogens were retrospectively evaluated, findings were recorded and compared between the two groups.
Compared to non-COVID-19, COVID-19 patients were more likely to have a peripheral (60.5% vs. 23.8%, p < 0.001) and bilateral distribution (72.3% vs. 41.3%, p < 0.001), patchy consolidations (45% vs. 28.9%, p = 0.021), ground glass opacity (GGO) (94.2% vs. 83.1%, p = 0.011), crazy paving patterns (55% vs. 31.3%, p < 0.001); but less likely to have centrilobular nodules (15% vs. 62.7%, p < 0.001), pleural effusion (3.3% vs. 10.8%, p = 0.032), multifocal consolidations (7.5% vs. 21.7%, p = 0.003), and random distribution (1.7% vs. 46.3%, p < 0.001).
There were significant differences between the CT patterns of patients with COVID-19 and other atypical pneumonia. The presence of patchy consolidations, GGO, crazy paving patterns with typical peripheral, bilateral distribution, and absence of centrilobular nodules, pleural effusion, and multifocal consolidations may help to differentiate COVID-19 from atypical pneumonia.
计算机断层扫描（CT）在快速诊断、治疗和管理下呼吸道感染方面具有重要作用。本研究旨在探讨急诊收治的新型冠状病毒病（COVID-19）与非 COVID-19 患者的胸部 CT 影像特征。
回顾性分析 120 例经逆转录-聚合酶链反应（RT-PCR）检测 SARS-CoV-2 阳性的患者的 CT 特征，以及 83 例 RT-PCR 检测 SARS-CoV-2 阴性但呼吸道样本其他呼吸道病原体检测阳性的患者的 CT 特征，记录并比较两组患者的 CT 表现。
与非 COVID-19 患者相比，COVID-19 患者更易出现外周性（60.5% vs. 23.8%，p < 0.001）和双侧分布（72.3% vs. 41.3%，p < 0.001）、斑片状实变（45% vs. 28.9%，p = 0.021）、磨玻璃密度影（GGO）（94.2% vs. 83.1%，p = 0.011）、铺路石征（55% vs. 31.3%，p < 0.001），但更不易出现小叶中心结节（15% vs. 62.7%，p < 0.001）、胸腔积液（3.3% vs. 10.8%，p = 0.032）、多灶性实变（7.5% vs. 21.7%，p = 0.003）和随机分布（1.7% vs. 46.3%，p < 0.001）。
COVID-19 与非 COVID-19 患者的 CT 表现存在显著差异。斑片状实变、GGO、铺路石征伴典型的外周性、双侧分布、小叶中心结节、胸腔积液和多灶性实变的缺失有助于鉴别 COVID-19 与非 COVID-19。
