初产妇工作状况与端粒长度的关系：一项为期 1 年的前瞻性研究。
Working Status of First-Time Postpartum Mothers and Telomere Length-A 1-Year Prospective Study.
机构信息
From the School of Public Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Mount Carmel, Haifa, Israel (N.H.-K., O.B.-E.); Health Systems Management Department, The Max Stern Yezreel Valley College, Yezreel Valley, Israel (S.B.); Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA (E.E.); Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA (J.L.); and Bnei Zion Medical Center, Haifa, Israel (L.S.).
出版信息
J Occup Environ Med. 2023 Dec 1;65(12):1036-1044. doi: 10.1097/JOM.0000000000002966. Epub 2023 Sep 12.
OBJECTIVE
Transitioning to motherhood can create work family conflicts affecting mothers' health. Although employment is generally associated with longer telomeres, this may diminish during the early years of child-rearing. This study aimed to assess the impact of work reentry on telomere length (TL) among first-time mothers.
METHODS
In this 1-year prospective study, a total of 103 first-time postpartum mothers participated from two medical institutions in Northern Israel; they completed validated questionnaires, reported their current working status, and provided dried blood spots measuring TL.
RESULTS
We found that working status significantly predicted change in TL and was negatively correlated with change in TL over time (β = -0.245; 95% confidence interval, -0.169, -0.018; P = 0.016).
CONCLUSIONS
Identifying ideal timing of work reentry is recommended for first-time postpartum mother's optimal health and TL.
目的
成为母亲可能会引发工作与家庭冲突，影响母亲的健康。尽管一般来说，就业与端粒较长有关，但在育儿的早期，这种情况可能会减少。本研究旨在评估初为人母者重新工作对端粒长度（TL）的影响。
方法
在这项为期 1 年的前瞻性研究中，共有 103 名来自以色列北部两家医疗机构的初产妇参与；她们完成了经验证的问卷，报告了当前的工作状况，并提供了测量 TL 的干血斑。
结果
我们发现，工作状况显著预测 TL 的变化，且与 TL 随时间的变化呈负相关（β=-0.245；95%置信区间，-0.169，-0.018；P=0.016）。
结论
建议初为人母者重新工作的理想时机，以实现其最佳健康和 TL。
Zotero 插件