Division of Plastic and Reconstructive Surgery, Strong Memorial Hospital, University of Rochester Medical Center, NY, USA.
Division of Surgical Oncology, Department of Surgery, Pluta Cancer Center, Wilmot Cancer Center, University of Rochester Medical Center, NY, USA.
Am J Surg. 2024 Feb;228:185-191. doi: 10.1016/j.amjsurg.2023.09.023. Epub 2023 Sep 20.
Few studies have reported the outcomes of LDF and immediate fat transfer (LIFT) during breast reconstruction. The aim of this study was to compare the perioperative outcomes and complications of LIFT and standard LDF (without immediate fat transfer) for breast reconstruction.
We retrospectively reviewed charts from patients undergoing autologous breast reconstruction after total mastectomy between 2011 and 2021. We compared intraoperative and postoperative outcomes between groups.
One hundred nineteen reconstructions (61.02%) were performed with LIFT, while seventy-six (38.98%) were performed with standard LDF. The median volume of total fat transferred during LIFT was 125-cc [110-170 cc]. The rates of donor site wound disruption (23.7% versus 12.6%, p = 0.044) were higher using the standard LDF compared to LIFT. Reconstructions performed with LIFT (HR 4.01, p < 0.001) were found to be associated with secondary fat grafting procedures.
LIFT is a safe procedure to enhance the volume of LDF in patients desiring autologous reconstruction without increasing recipient-site morbidity. On a time-to-event analysis, LIFT was associated with the requirement of further revision procedures using secondary fat grafting.
很少有研究报道过乳房重建中 LDF 和即刻脂肪转移(LIFT)的结果。本研究旨在比较 LIFT 和标准 LDF(不立即进行脂肪转移)在乳房重建中的围手术期结果和并发症。
我们回顾性分析了 2011 年至 2021 年间因全乳切除术后接受自体乳房重建的患者的病历。我们比较了两组患者的术中及术后结果。
119 例(61.02%)采用 LIFT 进行重建,76 例(38.98%)采用标准 LDF 进行重建。LIFT 中转移的总脂肪量中位数为 125-170cc[110-170cc]。标准 LDF 组的供区伤口破裂率(23.7%比 12.6%,p=0.044)高于 LIFT 组。LIFT 组(HR4.01,p<0.001)进行重建与二次脂肪移植术相关。
LIFT 是一种安全的手术,可以在不增加受区发病率的情况下增加 LDF 的体积,为渴望自体重建的患者提供帮助。在时间事件分析中,LIFT 与使用二次脂肪移植进行进一步修正手术的需求相关。