Ma Yucheng, Yang E, Lin Wentao
Department of Burn and Plastic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
J Cosmet Dermatol. 2024 Feb;23(2):607-613. doi: 10.1111/jocd.16011. Epub 2023 Sep 27.
The deepening of the nasolabial fold (NLF) is a common occurrence during the aging process, necessitating the development of an objective method to evaluate changes in NLFs. The objective of our study was to introduce a method of depth deviation based on three-dimensional (3D) image for evaluating the efficacy of hyaluronic acid (HA) injection in correcting NLFs.
Between May 2019 and November 2019, we recruited 56 Chinese volunteers with moderate to severe NLFs for this study. The participants received HA injections and were followed up for a period of 12 months. Pre and posttreatment, we collected the Wrinkle Severity Rating Scale (WSRS) scores and 3D images. To assess the efficacy of NLF correction, we used the maximum value of depth deviation (MVD) based on 3D images and the Global Aesthetic Improvement Scale (GAIS) score. Additionally, we compared the relationship between MVD and other clinical parameters.
Fifty-four female participants completed the study and were included in the analysis. The HA injection resulted in a significant decrease in NLF severity (p < 0.05). One month after the injection, the average GAIS score was 4.72 ± 0.45, and the average MVD was 2.10 ± 0.56 mm. Both the GAIS score and the average MVD exhibited a decline over time during the follow-up period, with the average MVD showing a significant correlation with the GAIS score at all time points (p < 0.05).
Using 3D technology, we demonstrated that the quantitative data provided by MVD can serve as an objective method for evaluating the correction of NLFs.
鼻唇沟加深是衰老过程中的常见现象，因此需要开发一种客观方法来评估鼻唇沟的变化。本研究的目的是引入一种基于三维（3D）图像的深度偏差方法，以评估透明质酸（HA）注射矫正鼻唇沟的效果。
2019年5月至2019年11月，我们招募了56名患有中度至重度鼻唇沟的中国志愿者参与本研究。参与者接受了HA注射，并进行了为期12个月的随访。在治疗前后，我们收集了皱纹严重程度评分量表（WSRS）得分和3D图像。为了评估鼻唇沟矫正的效果，我们使用了基于3D图像的深度偏差最大值（MVD）和整体美学改善量表（GAIS）得分。此外，我们比较了MVD与其他临床参数之间的关系。
54名女性参与者完成了研究并纳入分析。HA注射使鼻唇沟严重程度显著降低（p < 0.05）。注射后1个月，平均GAIS评分为4.72±0.45，平均MVD为2.10±0.56毫米。在随访期间，GAIS评分和平均MVD均随时间下降，平均MVD在所有时间点与GAIS评分均显示出显著相关性（p < 0.05）。
使用3D技术，我们证明了MVD提供的定量数据可作为评估鼻唇沟矫正效果的客观方法。
