使用不同抗氧化剂的牛体外成熟和胚胎生产的当前进展：综述
Current Advances in Bovine In Vitro Maturation and Embryo Production Using Different Antioxidants: A Review.
作者信息
Naspinska Roksana, Moreira da Silva Maria Helena, Moreira da Silva Fernando
机构信息
Animal Reproduction, Centro de Investigação e Tecnologia Agrária dos Açores IITA-A, Faculty of Agricultural and Environmental Sciences, University of the Azores, 9701-851 Angra do Heroísmo, Portugal.
出版信息
J Dev Biol. 2023 Aug 29;11(3):36. doi: 10.3390/jdb11030036.
In vitro maturation (IVM) is one of the most important steps in in vitro embryo production (IVEP). It is a complicated procedure in which nuclear and cytoplasmatic changes in oocytes appear. In order to carry out the in vitro maturation procedure correctly, it is necessary to provide the oocytes with as close to a natural (in vivo) environment as possible. Many factors contribute to the overall poor quality of in vitro-matured oocytes. One important factor may be oxidative stress (OS). The generation of oxidants, such as reactive oxygen species, is common under culture conditions. The solution for OC treatment and prevention is antioxidants. In the last 5 years, many studies have examined different antioxidants and their effects on in vitro maturation of oocytes and embryo production. The aim of this systematic review was to present the achievements of scientific research in the last five years, in which the effects of many antioxidants were tested on bovine oocyte maturation and embryo production.
体外成熟（IVM）是体外胚胎生产（IVEP）中最重要的步骤之一。这是一个复杂的过程，其中卵母细胞会出现核和细胞质变化。为了正确进行体外成熟过程，有必要为卵母细胞提供尽可能接近自然（体内）的环境。许多因素导致体外成熟卵母细胞的整体质量较差。一个重要因素可能是氧化应激（OS）。在培养条件下，氧化剂如活性氧的产生很常见。针对氧化应激的治疗和预防方法是使用抗氧化剂。在过去5年中，许多研究检测了不同的抗氧化剂及其对卵母细胞体外成熟和胚胎生产的影响。本系统综述的目的是介绍过去五年的科研成果，其中测试了多种抗氧化剂对牛卵母细胞成熟和胚胎生产的影响。
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