Rolles K, Calne R Y, McMaster P
Transplantation. 1979 Jul;28(1):44-6. doi: 10.1097/00007890-197907000-00010.
The fate of 42 kidney grafts taken from heart-beating, ventilated donors at the same time as removal of the liver for allografting is reported, and is compared with 50 kidney grafts taken from heart-beating, ventilated donors whose ventilators were electively switched off either during or immediately before kidney removal. The fate of 32 kidney grafts taken from donors classified as "dead on arrival" at the admitting hospital is also reported. Onset of life-supporting graft function was significantly earlier among kidneys from the "liver donor" group. Consequently, immediate postoperative dialysis requirements were significantly less in recipients of this group of kidneys. Early graft survival, the incidence of graft primary nonfunction, failure of first and second kidney grafts, and recipient survival were not significantly different when comparing liver donor and "ventilator switch off" kidneys. No constant relationship was apparent in any donor group between graft fate and the anoxic and ischaemic times the graft was exposed to during organ removal and reimplantation.
报告了42例在进行肝脏移植手术同时取自心跳、通气供体的肾移植情况,并与50例取自心跳、通气供体的肾移植情况进行比较,后者的呼吸机在取肾期间或取肾前即刻被选择性关闭。还报告了32例取自入院时被归类为“到达医院时已死亡”供体的肾移植情况。“肝脏供体”组的肾移植中,维持生命的移植肾功能开始时间明显更早。因此,该组肾移植受者术后即刻的透析需求明显更少。比较肝脏供体肾和“呼吸机关闭”肾时,早期移植肾存活、移植肾原发性无功能发生率、首次和第二次肾移植失败率以及受者存活率并无显著差异。在任何供体组中,移植肾命运与器官切除和再植入期间移植肾所经历的缺氧和缺血时间之间均无明显的固定关系。