Millet Bruno, Mouchabac Stéphane, Robert Gabriel, Maatoug Redwan, Dondaine Thibaut, Ferreri Florian, Bourla Alexis
Service de Psychiatrie Adulte de la Pitié-Salpêtrière, Institut du Cerveau, ICM, Sorbonne Université, AP-HP, 75013 Paris, France.
ICRIN Psychiatry (Infrastructure of Clinical Research in Neurosciences-Psychiatry), Brain Institute (ICM), INSERM, CNRS, 75013 Paris, France.
Brain Sci. 2023 Sep 15;13(9):1332. doi: 10.3390/brainsci13091332.
The current literature review aimed to evaluate the effectiveness of rTMS on the precuneus as a potential treatment for Alzheimer's disease (AD). Although the number of studies specifically targeting the precuneus is limited, the results from this review suggest the potential benefits of this approach. Future studies should focus on exploring the long-term effects of rTMS on the precuneus in Alzheimer's disease patients, as well as determining the optimal stimulation parameters and protocols for this population. Additionally, investigating the effects of rTMS on the precuneus in combination with other brain regions implicated in AD may provide valuable insights into the development of effective treatment for this debilitating neurodegenerative disorder.
当前的文献综述旨在评估重复经颅磁刺激(rTMS)作用于楔前叶作为阿尔茨海默病(AD)潜在治疗方法的有效性。尽管专门针对楔前叶的研究数量有限,但该综述的结果表明了这种方法的潜在益处。未来的研究应侧重于探索rTMS对阿尔茨海默病患者楔前叶的长期影响,以及确定该人群的最佳刺激参数和方案。此外,研究rTMS联合AD中涉及的其他脑区对楔前叶的影响,可能会为这种使人衰弱的神经退行性疾病的有效治疗方法的开发提供有价值的见解。