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院前急性心力衰竭肺部超声:对诊断和治疗的影响。

Prehospital lung ultrasound in acute heart failure: Impact on diagnosis and treatment.

机构信息

Department of Emergency Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Department of Emergency Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.

出版信息

Acad Emerg Med. 2024 Jan;31(1):42-48. doi: 10.1111/acem.14811. Epub 2023 Oct 19.

DOI:10.1111/acem.14811
PMID:37772384
Abstract

OBJECTIVE

Patients with acute heart failure (AHF) are commonly misdiagnosed and undertreated in the prehospital setting. These delays in diagnosis and treatment have a direct negative impact on patient outcomes. The goal of this study was to determine the diagnostic accuracy of paramedics with and without the use of lung ultrasound (LUS) for the diagnosis of AHF in patients with dyspnea in the prehospital setting. Secondarily, we assessed LUS impact on rate of and time to initiation of HF therapies.

METHODS

This was a prospective interventional study on a consecutive sample of patients transported to the hospital by one emergency medical services agency. Adult patients (>18 years) with a chief complaint of dyspnea were included. LUS was performed by trained paramedics and was defined as positive for AHF if both anterior-superior lung zones had greater than or equal to three B-lines or bilateral B-lines were visualized on a four-view protocol. Paramedic diagnosis was compared to hospital discharge diagnosis which served as the criterion standard.

RESULTS

Of the 264 included patients, 94 (35%) had a final diagnosis of AHF. Forty total patients had a LUS performed; 17 of these patients had a final diagnosis of AHF. Sensitivity and specificity for AHF by paramedics were 23% (95% confidence interval [CI] 0.14-0.34) and 97% (95% CI 0.92-0.99) without LUS and 71% (95% CI 0.44-0.88) and 96% (95% CI 0.76-0.99) with the use of LUS. In the 94 patients with AHF, 14% (11/77) received HF therapy prehospital without the use of LUS and 53% (9/17) with the use of LUS. LUS improved frequency of treatment by 39%. Median time to treatment was 21 min with LUS and 169 min without.

CONCLUSIONS

LUS improved paramedic sensitivity and accuracy for diagnosing AHF in the prehospital setting. LUS use led to higher rates of prehospital HF therapy initiation and significantly decreased time to treatment.

摘要

目的

急性心力衰竭(AHF)患者在院前常被误诊和治疗不足。这些诊断和治疗的延误对患者的预后有直接的负面影响。本研究的目的是确定在院前有或没有使用肺部超声(LUS)的情况下,护理人员对呼吸困难的 AHF 患者的诊断准确性。其次,我们评估了 LUS 对 HF 治疗开始率和时间的影响。

方法

这是一项对一家紧急医疗服务机构转运至医院的连续患者样本进行的前瞻性干预研究。纳入的成年患者(>18 岁)主诉呼吸困难。由经过培训的护理人员进行 LUS 检查,如果前上肺区有大于或等于三条 B 线或四视图协议上可见双侧 B 线,则将 LUS 定义为 AHF 阳性。将护理人员的诊断与出院诊断进行比较,出院诊断作为金标准。

结果

在纳入的 264 例患者中,94 例(35%)最终诊断为 AHF。40 例患者进行了 LUS 检查;其中 17 例患者最终诊断为 AHF。无 LUS 时,护理人员对 AHF 的敏感性和特异性分别为 23%(95%CI 0.14-0.34)和 97%(95%CI 0.92-0.99),使用 LUS 时分别为 71%(95%CI 0.44-0.88)和 96%(95%CI 0.76-0.99)。在 94 例 AHF 患者中,有 14%(11/77)未使用 LUS 在院前接受 HF 治疗,而使用 LUS 者为 53%(9/17)。LUS 将治疗的频率提高了 39%。使用 LUS 的中位治疗时间为 21 分钟,而未使用 LUS 的中位治疗时间为 169 分钟。

结论

LUS 提高了院前护理人员诊断 AHF 的敏感性和准确性。使用 LUS 可提高院前 HF 治疗的启动率,并显著缩短治疗时间。

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