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从卫生工作者角度看癌症疼痛管理中阿片类镇痛药获取障碍的系统评价

Systematic Review on Barriers to Access Opioid Analgesics for Cancer Pain Management from the Health Worker Perspective.

机构信息

Department of Palliative Medicine, Medical Faculty, RWTH University Aachen, Aachen, Germany.

International Association for Hospice and Palliative Care (IAHPC), Houston, Texas, USA.

出版信息

J Pain Palliat Care Pharmacother. 2023 Dec;37(4):324-335. doi: 10.1080/15360288.2023.2257674. Epub 2023 Nov 28.

Abstract

The increasing incidence of oncological diseases creates a corresponding need for effective cancer pain management (CPM). The lack of access to and availability of opioid analgesics in most countries leads to avoidable suffering. This systematic review aims to identify barriers to accessing opioids, as described in literature that reflects the perspective of health-care workers. A systematic literature search was performed in May 2018 and updated in December 2022, using search terms related to "cancer pain," "opioid analgesics," "access," and "health-care personnel." Medline, Embase, and PsycInfo were searched. Forty-two studies met the inclusion criteria. Principal barriers that have hindered licit access to medical opioids include regulatory, systemic, educational, patient-related, and societal. These barriers are rooted in a lack of adequate education about the importance and significance of appropriate CPM. Barriers were often mutually reinforcing. A interdisciplinary approach is required to overcome them. This research contributes to the important global health issue of unduly limited access to opioid analgesics. It provides interdisciplinary solutions in terms of guidelines to ensure that governments respect, protect, and fulfill the right to the highest attainable standard of health, which includes the relief of severe pain.

摘要

不断增加的肿瘤发病率导致对有效癌症疼痛管理(CPM)的相应需求不断增加。在大多数国家,阿片类镇痛药的可及性和可获得性不足,导致了可避免的痛苦。本系统评价旨在确定文献中描述的获取阿片类药物的障碍,这些文献反映了医疗保健工作者的观点。2018 年 5 月进行了系统的文献检索,并于 2022 年 12 月进行了更新,使用了与“癌症疼痛”、“阿片类镇痛药”、“获取”和“医疗保健人员”相关的搜索词。检索了 Medline、Embase 和 PsycInfo。符合纳入标准的有 42 项研究。主要的障碍包括监管、系统、教育、患者相关和社会方面,这些障碍阻碍了合法获得医用阿片类药物。这些障碍源于对适当 CPM 的重要性和意义的充分教育的缺乏。障碍往往相互加强。需要采取跨学科的方法来克服这些障碍。这项研究有助于解决全球范围内阿片类镇痛药获取受限的重要健康问题。它提供了跨学科的解决方案,包括指南,以确保政府尊重、保护和履行享有能达到的最高健康标准的权利,其中包括缓解严重疼痛。

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