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超声引导与传统透视引导下经皮腰椎间盘切除术治疗神经根病。一项随机对照试验的荟萃分析。

Ultrasound-Guided Versus Conventional Fluoroscopy-Guided Epidural Injection for Radiculopathy. A Meta-Analysis of Randomized Controlled Trials.

机构信息

Department of Surgery, Holy Family Hospital, Rawalpindi Medical University, Rawalpindi, Pakistan.

Department of Surgery, Holy Family Hospital, Rawalpindi Medical University, Rawalpindi, Pakistan.

出版信息

World Neurosurg. 2023 Dec;180:203-212.e4. doi: 10.1016/j.wneu.2023.09.088. Epub 2023 Sep 27.

Abstract

BACKGROUND

Radiculopathy, a painful condition due to the irritation of a spinal nerve root, is a common neurosurgical presentation. Apart from its conventional treatment with pain killers and surgical management, it can also be managed with epidural steroid injections (ESIs). The objective of this study is to compare ultrasonography (USG) guidance with conventional fluoroscopy (FL) guidance for ESIs to treat radiculopathy.

METHODS

PubMed, Embase, Clinicaltrials.gov, and Cochrane were systematically searched and randomized controlled trials comparing USG with conventional FL for ESIs in the case of radiculopathy were included. Web Revman was used for data analysis.

RESULTS

The Literature search resulted in 640 studies, of which 7 studies were included in this meta-analysis after extensive screening. There was no statistically significant difference in pain reduction between USG and FL groups especially in the case of lumbosacral spinal level at 1 month [mean difference -0.12 (-0.47-0.23)] and at 3 months [mean difference 0.73 (-1.49, 2.96)]. Similarly, functional improvement after ESIs was comparable between the 2 groups. The Risk of inadvertent vascular puncture in USG-guided ESIs was lower as compared to conventional FL-guided ESIs [odds ratio 0.21 (0.07, 0.64)]. Furthermore, the procedure time in the USG group was also significantly lower as compared to FL group.

CONCLUSION

USG-guided ESIs are not only comparable to conventional FL-guided ESIs in terms of pain control and functional improvement, particularly evident at the lumbosacral spinal level, but also have a lower risk of inadvertent vascular puncture.

摘要

背景

神经根病是一种由于脊神经根受到刺激而引起的疼痛病症,是一种常见的神经外科病症。除了常规的止痛药和手术治疗外,它还可以通过硬膜外类固醇注射(ESI)来治疗。本研究的目的是比较超声(USG)引导与传统透视(FL)引导ESI 治疗神经根病的效果。

方法

系统检索 PubMed、Embase、Clinicaltrials.gov 和 Cochrane 数据库,纳入比较 USG 与传统 FL 引导 ESI 治疗神经根病的随机对照试验。使用 Web Revman 进行数据分析。

结果

文献检索得到 640 项研究,经过广泛筛选后,有 7 项研究纳入本荟萃分析。USG 组和 FL 组在 1 个月时(平均差值-0.12,-0.47-0.23)和 3 个月时(平均差值 0.73,-1.49,2.96)的疼痛缓解方面无统计学差异。同样,ESI 治疗后两组的功能改善也相当。与传统 FL 引导 ESI 相比,USG 引导 ESI 中无意血管穿刺的风险较低[比值比 0.21(0.07,0.64)]。此外,USG 组的操作时间也明显短于 FL 组。

结论

USG 引导 ESI 在控制疼痛和改善功能方面与传统 FL 引导 ESI 相当,尤其是在腰骶段更为明显,而且无意血管穿刺的风险也较低。

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