Arab Suha, Binmahfooz Saleh, Abualsaud Renad M, Basuliman Alaa A, Qurain Roba, AlSaidlani Rawan H, Alsharif Shaker, Alsaiari Maha, Awami Hadeel
Department of Obstetrics and Gynecology, King Abdulaziz University Hospital, Jeddah, SAU.
Department of Medicine, King Abdulaziz University, Jeddah, SAU.
Cureus. 2023 Aug 28;15(8):e44273. doi: 10.7759/cureus.44273. eCollection 2023 Aug.
Background Diabetes is characterized by elevated blood glucose levels due to inadequate insulin production or abnormalities in cellular activity. Gestational diabetes mellitus (GDM) is one of the most prominent indicators of type 2 diabetes mellitus (T2DM), which develops in pregnant women whose pancreatic function is insufficient to control the insulin resistance associated with pregnancy. Moreover, it is the most common metabolic disorder, with the majority of cases beginning in the second or third trimester of pregnancy and affecting up to 25% of pregnant women. Objectives The objective of this study was to identify factors associated with postpartum T2DM screening in women with GDM at King Abdulaziz University Hospital (KAUH) between 2010 and 2022. The secondary objective was to assess the factors associated with providing information to the patients about the risks of increased blood glucose and postpartum lifestyle modification. Methods We conducted a retrospective cross-sectional study at KAUH to investigate potential factors associated with postpartum screening for T2DM. Out of 564 patients diagnosed with GDM between 2020 and 2022, we included 200 women aged over 18 years with a history of GDM, as they met the inclusion criteria for our study. Patients younger than 18 years with missing or incomplete baseline characteristics were excluded. Data were analyzed using SPSS Statistics version 21 (IBM Corp. Released 2012. IBM SPSS Statistics for Windows, Version 21.0. Armonk, NY: IBM Corp.), and p-value <0.05 was considered significant. Results A total of 200 postpartum women with GDM were included in this study. Their mean age was 35.02±5.2 years. Many of them had a family history of diabetes (83.0%) and a previous diagnosis of GDM (60.5%). The patients who performed glucose testing six weeks after birth were previously diagnosed with GDM (37.0%) or with a family history of diabetes (45.5%). The significant variables in this analysis were mothers having frequent postpartum hospital follow-up visits (P<0.001), mothers with gestational weight gain (P=0.018), those who were informed about the risks of increased blood glucose (P=0.011), and those who were informed about plans for postpartum glucose screening (P=0.002). The mothers with a previous history of GDM were the highest to be informed of the risks of elevated blood glucose. Conclusion Frequent postpartum hospital follow-up visits, gestational weight gain, knowledge of the risks of elevated blood sugar, and postpartum glucose screening plans were all associated with postpartum glucose testing rates among women with GDM in Saudi Arabia.
糖尿病的特征是由于胰岛素分泌不足或细胞活动异常导致血糖水平升高。妊娠期糖尿病(GDM)是2型糖尿病(T2DM)最显著的指标之一,它发生在胰腺功能不足以控制与妊娠相关的胰岛素抵抗的孕妇中。此外,它是最常见的代谢紊乱疾病,大多数病例始于妊娠中期或晚期,影响多达25%的孕妇。
本研究的目的是确定2010年至2022年期间在阿卜杜勒阿齐兹国王大学医院(KAUH)患有GDM的女性产后T2DM筛查的相关因素。次要目的是评估与向患者提供血糖升高风险和产后生活方式改变信息相关的因素。
我们在KAUH进行了一项回顾性横断面研究,以调查与产后T2DM筛查相关的潜在因素。在2020年至2022年期间诊断为GDM的564例患者中,我们纳入了200名年龄超过18岁且有GDM病史的女性,因为她们符合我们研究的纳入标准。排除年龄小于18岁且基线特征缺失或不完整的患者。使用SPSS Statistics 21版(IBM公司。2012年发布。适用于Windows的IBM SPSS Statistics,版本21.0。纽约州阿蒙克:IBM公司)进行数据分析,p值<0.05被认为具有统计学意义。
本研究共纳入200名患有GDM的产后女性。她们的平均年龄为35.02±5.2岁。她们中的许多人有糖尿病家族史(83.0%)和既往GDM诊断史(60.5%)。产后六周进行血糖检测的患者既往诊断为GDM(37.0%)或有糖尿病家族史(45.5%)。该分析中的显著变量是产后经常到医院随访的母亲(P<0.001)、有妊娠期体重增加的母亲(P=0.018)、被告知血糖升高风险的母亲(P=0.011)以及被告知产后血糖筛查计划的母亲(P=0.002)。既往有GDM病史的母亲被告知血糖升高风险的比例最高。
产后经常到医院随访、妊娠期体重增加、对血糖升高风险的了解以及产后血糖筛查计划均与沙特阿拉伯患有GDM的女性产后血糖检测率相关。