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导致快速进展性脊髓病并酷似急性横贯性脊髓炎的胸段硬膜外动静脉畸形:一例报告

Thoracic epidural arteriovenous malformation causing rapidly progressive myelopathy and mimicking an acute transverse myelitis: A case report.

作者信息

Yuan Hao, Pi Yu, Zhou Hong-Su, Wang Chong, Liu Wei, Niu Yong-Min, Lan Yang, Chen Dong, Liu Shi-Ran, Xiao Shun-Wu

机构信息

Department of Orthopedics Affiliated Hospital of Zunyi Medical University Zunyi Guizhou China.

Institute of Neuroscience Kunming Medical University Kunming Yunnan China.

出版信息

Ibrain. 2022 Oct 26;8(4):492-499. doi: 10.1002/ibra.12070. eCollection 2022 Winter.

DOI:10.1002/ibra.12070
PMID:37786589
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10528776/
Abstract

Clinical symptoms of spinal arteriovenous malformations (AVMs) combined with acute spontaneous hemorrhage lack specificity, which leads to misdiagnosis and delays treatment. The current study aimed to analyze the causes of misdiagnosis and review the key points of diagnosis and treatment. We presented an extremely rare case of a 25-year-old man whose clinical characteristics mimicked acute transverse myelitis, suffering from rapidly and repeatedly progressive myelopathy with a mass. The pathological diagnosis of the mass was AVM; symptom-based surgical treatment with posterior decompression and the removal of epidural AVMs during the postoperative 12-month follow-up period were performed. The manual muscle testing grade score of the proximal and distal muscles in both lower limbs improved from 1 to 5, and the American Spinal Injury Association motor and sensation grade score improved from B to E. In the case of sudden or progressive spinal cord injury of unknown cause and acute spinal cord dysfunction, there might be a misdiagnosis. The key to a differential diagnosis is to take into account AVMs, and spontaneous hemorrhages and hematomas should also be suspected. Angiography and magnetic resonance imaging are very important for the diagnosis of AVM, and we hope to enhance clinicians' understanding of and vigilance for such diseases.

摘要

脊髓动静脉畸形(AVM)合并急性自发性出血的临床症状缺乏特异性,易导致误诊并延误治疗。本研究旨在分析误诊原因并回顾诊断与治疗要点。我们报告了一例极为罕见的病例,一名25岁男性,其临床特征类似急性横贯性脊髓炎,患有快速且反复进展的脊髓病并伴有肿块。肿块的病理诊断为AVM;采取了基于症状的手术治疗,包括后路减压,并在术后12个月随访期内切除硬膜外AVM。双下肢近端和远端肌肉的徒手肌力测试分级评分从1级提高到5级,美国脊髓损伤协会运动和感觉分级评分从B级提高到E级。对于原因不明的突发或进行性脊髓损伤及急性脊髓功能障碍,可能存在误诊。鉴别诊断的关键是要考虑到AVM,同时也应怀疑自发性出血和血肿。血管造影和磁共振成像对AVM的诊断非常重要,我们希望提高临床医生对这类疾病的认识和警惕性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0ac/10528776/b8dc510a212f/IBRA-8-492-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0ac/10528776/af80980ff680/IBRA-8-492-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0ac/10528776/a8ea2514c515/IBRA-8-492-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0ac/10528776/3add3bc615a2/IBRA-8-492-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0ac/10528776/6d6c2a58563b/IBRA-8-492-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0ac/10528776/b8dc510a212f/IBRA-8-492-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0ac/10528776/af80980ff680/IBRA-8-492-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0ac/10528776/a8ea2514c515/IBRA-8-492-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0ac/10528776/3add3bc615a2/IBRA-8-492-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0ac/10528776/6d6c2a58563b/IBRA-8-492-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0ac/10528776/b8dc510a212f/IBRA-8-492-g005.jpg

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