Kang Lana, Victoria Christian, Desai Khusboo, Nguyen Joseph, Lee Steve K, Mancuso Carol A
Hand and Upper Extremity Service, Hospital for Special Surgery, 535 E 70th St, New York, NY 10021, USA.
Biostatistics Core, Hospital for Special Surgery, 535 E 70th St, New York, NY 10021, USA.
J Hand Surg Glob Online. 2023 Jun 15;5(5):655-660. doi: 10.1016/j.jhsg.2023.05.001. eCollection 2023 Sep.
With trapeziometacarpal osteoarthritis (TMC OA), the relationship between disease severity and pretreatment dysfunction, patient expectations, and preferred patient treatment and management remains unclear. This study aimed to assess the association between functional status, pretreatment expectations, and demographic and clinical characteristics of TMC OA patients who decide to undergo operative management.
Patients diagnosed with TMC OA (n = 96) were administered the Thumb Arthritis Expectations Survey and the Brief Michigan Hand Questionnaire (bMHQ) during their initial office visit. Demographic data (sex, age, race, education level, marital status, comorbidities, and hand dominance) and clinical characteristics (prior injury, and therapeutic interventions including splinting, steroid injections, therapy, and anti-inflammatory medication) were collected. Multiple logistic regression was used to assess the association between surgical treatment and expectation scores.
Our logistic regression model found that lower bMHQ scores, high thumb arthritis expectation survey scores, and prior treatments for TMC OA were associated significantly with the surgical treatment of TMC OA. After controlling for all possible covariates, the odds of having surgery was 3.9 times higher among patients with high expectations (above median) compared to patients with low expectations (adjusted odds ratio [AOR], 3.9; 95% confidence interval [CI], 1.3-11.2). Patients with average function, as measured by bMHQ scores, were 74.5% less likely to elect for surgery than those with the lowest bMHQ (AOR, 0.3; 95% CI, 0.1-0.9). Patients treated previously with steroids were 13 times more likely to elect for surgery than those who were never treated for TMC arthritis (AOR,13.1; 95% CI, 2.2-77.0).
Patients with TMC OA who elect to proceed with surgical management have lower bMHQ (greater perceived dysfunction) and higher expectations, and have had prior treatment. Age was not a significant predictor of surgical management of TMC OA.
TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic IV.
在第一掌腕关节骨关节炎(TMC OA)中,疾病严重程度与治疗前功能障碍、患者期望以及患者偏爱的治疗和管理方式之间的关系仍不明确。本研究旨在评估决定接受手术治疗的TMC OA患者的功能状态、治疗前期望与人口统计学及临床特征之间的关联。
对诊断为TMC OA的患者(n = 96)在初次门诊时进行拇指关节炎期望调查和密歇根手功能简易问卷(bMHQ)评估。收集人口统计学数据(性别、年龄、种族、教育水平、婚姻状况、合并症和利手)及临床特征(既往损伤,以及包括夹板固定、类固醇注射、理疗和抗炎药物在内的治疗干预措施)。采用多因素逻辑回归分析评估手术治疗与期望得分之间的关联。
我们的逻辑回归模型发现,较低的bMHQ得分、较高的拇指关节炎期望调查得分以及既往TMC OA治疗与TMC OA的手术治疗显著相关。在控制所有可能的协变量后,高期望(高于中位数)患者接受手术的几率是低期望患者的3.9倍(调整优势比[AOR],3.9;95%置信区间[CI],1.3 - 11.2)。以bMHQ得分衡量,功能处于平均水平的患者选择手术的可能性比bMHQ得分最低的患者低74.5%(AOR,0.3;95% CI,0.1 - 0.9)。既往接受过类固醇治疗的患者选择手术的可能性是从未接受过TMC关节炎治疗患者的13倍(AOR,13.1;95% CI,2.2 - 77.0)。
选择进行手术治疗的TMC OA患者bMHQ得分较低(感觉功能障碍更严重)且期望较高,并且既往接受过治疗。年龄并非TMC OA手术治疗的显著预测因素。
研究类型/证据水平:预后性IV级。