Anderson Moores Veterinary Specialists, Part of Linnaeus Veterinary Limited, Winchester, Hampshire, UK.
Hamilton Specialists Referral, Part of IVC Evidensia, High Wycombe, Buckinghamshire, UK.
J Feline Med Surg. 2023 Oct;25(10):1098612X231199731. doi: 10.1177/1098612X231199731.
The aim of the study was to describe the patient demographics, clinicopathological features and presumptive or final diagnoses in cats with myelopathies between the T1 and T6 vertebrae.
This retrospective multicentre case study enrolled cases between 2015 and 2022 that were diagnosed with myelopathies between the T1 and T6 vertebrae as the primary cause for the presenting clinical signs.
A total of 21 cases matched the inclusion criteria, 13 males (11 castrated and 2 entire) and 8 spayed females (median age 93 months; range 5-192). Most of the cases presented with a chronic and progressive history (76% and 86%, respectively), with a median duration of 29 days (range 1-2880). At the time of presentation, 90% of the cases were localised to the T3-L3 spinal cord segments based on neurological examination. The most common underlying pathology was neoplasia (42.9%), followed by inflammatory (24%), anomalous (19%), degenerative (9.5%) and vascular (4.8%) disorders. The most common location was T3-T4 (29%), followed by T2-T3 and T5-T6 (19% each). The cutaneous trunci reflex was normal in 86% of the cases and most of the cases (71%) did not show spinal discomfort upon admission.
Neoplasia was the most common cause of cranial thoracic myelopathy in this study. The lack of pathognomonic clinical signs for this specific region highlights the importance of assessing the entire thoracolumbar region up to and including at least the T1 vertebra when investigating cases with signs consistent with a T3-L3 myelopathy.
本研究旨在描述 T1 至 T6 椎体之间患有脊髓病变的猫的患者人口统计学、临床病理学特征以及初步或最终诊断。
这项回顾性多中心病例研究纳入了 2015 年至 2022 年期间被诊断为 T1 至 T6 椎体之间的脊髓病变为主要临床表现的病例。
共有 21 例符合纳入标准，其中 13 例为雄性（11 例去势和 2 例完整），8 例为去势雌性（中位数年龄 93 个月；范围 5-192）。大多数病例呈慢性进行性病史（分别为 76%和 86%），中位数病程为 29 天（范围 1-2880）。在就诊时，根据神经学检查，90%的病例定位在 T3-L3 脊髓节段。最常见的潜在病理学是肿瘤（42.9%），其次是炎症（24%）、异常（19%）、退行性（9.5%）和血管（4.8%）疾病。最常见的部位是 T3-T4（29%），其次是 T2-T3 和 T5-T6（19%）。86%的病例皮节反射正常，大多数病例（71%）入院时没有表现出脊柱不适。
在本研究中，肿瘤是颅胸脊髓病变最常见的原因。该特定区域缺乏特征性的临床体征，这突出表明在调查表现出与 T3-L3 脊髓病变一致的体征的病例时，需要评估整个胸腰段区域，至少包括 T1 椎体。
