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女性行腹腔镜骶骨阴道固定术后年龄的影响:一项回顾性研究。

Effect of age in women undergoing laparoscopic sacrocolpopexy: A retrospective study.

机构信息

Department of Gynecology, MedStar, Baltimore, Maryland, USA.

Department of Gynecology, Emory Healthcare, Atlanta, Georgia, USA.

出版信息

Int J Gynaecol Obstet. 2024 Mar;164(3):1117-1124. doi: 10.1002/ijgo.15164. Epub 2023 Oct 5.

Abstract

OBJECTIVE

To determine whether elderly women (≥65 years) have an increased risk of complications and lower success when undergoing laparoscopic sacrocolpopexy (LSC) compared with younger women (<65 years).

METHODS

This was a retrospective study of all LSC procedures performed from August 2014 to February 2021 by a single urogynecologic surgeon in an academic affiliated hospital system. Charts were identified through procedure codes. Patient demographics, clinical, surgical, and postoperative data were collected. The primary outcome of this study was to compare complications associated with LSC, including intraoperative and postoperative complications. Secondary outcomes included subjective, objective, and composite success.

RESULTS

In total, 312 participants met the criteria. The mean age of the group who were younger than 65 years was 55.7 years (±6.5) and of the group aged 65 years or older was 69.3 years (±3.5). Racial demographics revealed no differences between the two groups. Patients aged 65 years or older had a statistically significant lower body mass index (calculated as weight in kilograms divided by the square of height in meters), a higher rate of hypertension, smaller genital hiatus, and a larger anterior vaginal wall prolapse compared with the younger cohort. They also less often underwent a posterior repair. No statistically significant differences were found with regards to intraoperative and postoperative complications, including 30-day re-admission, between the two age groups. Both groups had high anatomic success rates, with no significant difference (<65 = 96.3%; ≥65 = 98.4%; P = 0.326). Those aged younger than 65 years compared with those aged 65 years or older had lower subjective success that was not significantly different (<65 = 62.8%; ≥65 = 71.0; P = 0.134). Composite success was noted to reach the threshold of a statistically significant difference in the group aged younger than 65 years compared with those aged 65 years or older (60.1% vs 71.0%; P = 0.0499).

CONCLUSION

In this study, elderly patients did not have increased intraoperative and postoperative complications after undergoing LSC. Similar rates of anatomic and subjective success were also found with younger patients having a lower composite success. Proper candidates for LSC should not be excluded based upon age.

摘要

目的

确定与年轻女性(<65 岁)相比,老年女性(≥65 岁)接受腹腔镜骶骨阴道固定术(LSC)是否有更高的并发症风险和更低的成功率。

方法

这是一项回顾性研究,纳入了 2014 年 8 月至 2021 年 2 月期间由一位单名妇科泌尿医生在一家学术附属医院系统中进行的所有 LSC 手术。通过手术代码确定图表。收集患者的人口统计学、临床、手术和术后数据。本研究的主要结果是比较 LSC 相关并发症,包括术中及术后并发症。次要结果包括主观、客观和综合成功率。

结果

共有 312 名参与者符合标准。年龄小于 65 岁的组的平均年龄为 55.7 岁(±6.5),年龄为 65 岁或以上的组的平均年龄为 69.3 岁(±3.5)。种族人口统计学显示两组之间没有差异。65 岁或以上的患者体重指数(体重以千克为单位除以身高以米为单位的平方)显著较低,高血压发生率较高,生殖器裂孔较小,前阴道壁脱垂较大,与年轻队列相比。他们也较少进行后部修复。两组在术中及术后并发症方面无统计学差异,包括 30 天内再入院(<65 岁=30.0%;≥65 岁=30.0%;P=0.973)。两组的解剖学成功率均较高,无显著差异(<65 岁=96.3%;≥65 岁=98.4%;P=0.326)。与 65 岁或以上的患者相比,年龄小于 65 岁的患者主观成功率较低,但无统计学差异(<65 岁=62.8%;≥65 岁=71.0%;P=0.134)。与 65 岁或以上的患者相比,年龄小于 65 岁的患者复合成功率达到统计学显著差异的阈值(60.1%比 71.0%;P=0.0499)。

结论

在这项研究中,老年患者在接受 LSC 后并未增加术中及术后并发症。与年轻患者相比,两组的解剖学和主观成功率相似,而年轻患者的复合成功率较低。基于年龄,不应排除 LSC 的合适患者。

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