Patail Haris, Sharma Tanya, Aronow Wilbert, Haidry Syed Abbas
Department of Internal Medicine, University of Connecticut School of Medicine, Farmington, CT, USA.
Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, NY, USA.
Hosp Pract (1995). 2023 Oct;51(4):192-198. doi: 10.1080/21548331.2023.2268012. Epub 2023 Nov 16.
Though an infrequent cause of acute coronary syndrome, spontaneous coronary artery dissection is an increasingly recognized cardiovascular condition predominantly seen in middle-aged females. Its pathophysiology is defined by separation of coronary arterial wall layers which cause acute coronary syndrome-like presentations with relatively high recurrence rates. Overall, there is a lack of reported literature and understanding of the short- and long-term management for spontaneous coronary artery dissection. Therapeutic approaches include, but are not limited to, percutaneous coronary intervention, surgical revascularization, antithrombotic therapy, and beta-blocker therapy. There is a significant absence of randomized control trials to help guide both interventional and medical management for spontaneous coronary artery dissection. This review is aimed to review the current literature regarding risk factors and considerations for the short- and long-term management of spontaneous coronary artery dissection.
虽然自发性冠状动脉夹层是急性冠状动脉综合征的罕见病因，但它是一种日益被认识到的心血管疾病，主要见于中年女性。其病理生理学表现为冠状动脉壁层分离，导致类似急性冠状动脉综合征的表现，且复发率相对较高。总体而言，关于自发性冠状动脉夹层的短期和长期管理，缺乏相关文献报道和认识。治疗方法包括但不限于经皮冠状动脉介入治疗、外科血管重建术、抗血栓治疗和β受体阻滞剂治疗。目前严重缺乏随机对照试验来指导自发性冠状动脉夹层的介入治疗和药物治疗。本综述旨在回顾关于自发性冠状动脉夹层短期和长期管理的危险因素及注意事项的现有文献。
