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西班牙经桡动脉入路(TRA)与经股动脉入路(TFA)在神经血管介入治疗中对经济影响的早期探索。

Early exploration of the economic impact of transradial access (TRA) versus transfemoral access (TFA) for neurovascular procedures in Spain.

机构信息

Interventional Neuroradiology, Hospital General Universitari de Castelló, Castellon de la Plana, Spain.

Neuroradiology Unit, Department of Radiology, Hospital Álvaro Cunqueiro, Vigo, Spain.

出版信息

J Med Econ. 2023 Jan-Dec;26(1):1445-1454. doi: 10.1080/13696998.2023.2266956. Epub 2023 Nov 8.

Abstract

INTRODUCTION

Transfemoral access (TFA) is the primary access approach for neurointerventional procedures. Transradial access (TRA) is established in cardiology due to its lower complications, yet, it is at its early stages in neuroprocedures. This study performs an early exploration of the economic impact associated with the introduction of TRA in diagnostic and therapeutic neuroprocedures from the Spanish NHS perspective.

METHODS

An economic model was developed to estimate the cost and clinical implications of using TRA compared to TFA. Costs considered access-related, complications and recovery time costs obtained from local databases and experts' inputs. Clinical inputs were sourced from the literature. A panel of eight experts from different Spanish hospitals, validated or adjusted the values based on local experience. Hypothetical cohorts of 10,000 and 1000 patients were considered for diagnostic and therapeutic neuroprocedures respectively. Deterministic sensitivity analysis was performed.

RESULTS

TRA in diagnostic procedures was associated with lower costs with savings ranging between €486 and €157 depending on the TFA recovery time considered. TRA is estimated to lead to 158 fewer access-site complications. In therapeutic procedures, TRA resulted in 76.4 fewer complications and was estimated to be cost-neutral with an incremental cost of €21.56 per patient despite recovery times were not included for this group. Variation of the parameters in the sensitivity analysis did not change the direction of the results.

LIMITATIONS

Clinical data was obtained from literature validated by experts therefore results generalizability is limited. In therapeutic neuroprocedures, there is an experience imbalance between approaches and recovery times were not included hence the total impact is not fully captured.

CONCLUSIONS

The early economic model suggests that implementing TRA is associated with reduced costs and complications in diagnostic procedures. In therapeutic procedures, TRA lead to fewer complications and it is estimated to be cost-neutral, however its full potential still needs to be quantified.

摘要

简介

股动脉入路(TFA)是神经介入手术的主要入路方式。由于并发症较低,经桡动脉入路(TRA)在心脏病学中得到了确立,但在神经介入手术中仍处于早期阶段。本研究从西班牙国家卫生系统(NHS)的角度,对 TRA 在诊断和治疗性神经介入手术中的引入所带来的经济影响进行早期探索。

方法

本研究建立了一个经济模型,以评估与 TFA 相比使用 TRA 的成本和临床影响。所考虑的成本包括与入路相关的成本、并发症和恢复时间成本,这些成本来自当地数据库和专家的投入。临床数据则来自文献。来自西班牙不同医院的八位专家组成的小组根据当地经验验证或调整了这些值。考虑了诊断性和治疗性神经介入手术各 10000 例和 1000 例的假设队列。进行了确定性敏感性分析。

结果

TRA 在诊断性操作中与较低的成本相关,考虑到不同的 TFA 恢复时间,节约范围在 486 欧元至 157 欧元之间。TRA 估计会导致 158 例更少的入路部位并发症。在治疗性操作中,TRA 导致 76.4 例更少的并发症,并且尽管没有包括恢复时间,但估计在成本上是中性的,每位患者的增量成本为 21.56 欧元。敏感性分析中参数的变化并未改变结果的方向。

局限性

临床数据是从文献中获得的,经过专家验证,因此结果的推广性有限。在治疗性神经介入手术中,两种方法之间存在经验不平衡,并且没有包括恢复时间,因此尚未完全捕捉到总体影响。

结论

早期经济模型表明,在诊断性操作中实施 TRA 与降低成本和并发症相关。在治疗性操作中,TRA 导致的并发症更少,并且估计在成本上是中性的,但仍需要量化其全部潜力。

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