Fusillo Thomas F, Nguyen Michael
Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.
Medicine, College of Osteopathic Medicine, Des Moines University, Des Moines, USA.
Cureus. 2023 Sep 8;15(9):e44910. doi: 10.7759/cureus.44910. eCollection 2023 Sep.
Avascular necrosis (AVN) is a progressive disease characterized by bone death secondary to an interruption of the relevant vascular supply. While it is most common in pediatrics and later adulthood, it can occur at any age. This case describes a previously healthy man in his mid-twenties who presented with worsening hip pain. Imaging, including X-ray and magnetic resonance, revealed severe marrow edema and early collapse of the femoral head. The patient was also found to have a severely elevated low-density lipoprotein level, leading to the diagnosis of AVN due to familial hyperlipidemia. He received a total hip arthroplasty and was started on high-intensity statin therapy. This case highlights the importance of considering AVN in the young adult population with hip pain as well as the appropriate workup and treatment.
缺血性坏死(AVN)是一种进行性疾病,其特征是由于相关血管供应中断导致骨坏死。虽然它在儿科和成年后期最为常见,但可发生于任何年龄。本病例描述了一名二十多岁的既往健康男性,他出现了逐渐加重的髋部疼痛。包括X线和磁共振成像在内的影像学检查显示严重的骨髓水肿和股骨头早期塌陷。该患者还被发现低密度脂蛋白水平严重升高,导致因家族性高脂血症诊断为AVN。他接受了全髋关节置换术,并开始接受高强度他汀类药物治疗。本病例强调了在有髋部疼痛的年轻成年人群中考虑AVN以及进行适当检查和治疗的重要性。