Institute of Plant Protection, Jiangsu Academy of Agricultural Sciences , Nanjing, Jiangsu, China.
State Key Laboratory of Microbial Technology, Shandong University , Qingdao, Shandong, China.
Microbiol Spectr. 2023 Dec 12;11(6):e0118723. doi: 10.1128/spectrum.01187-23. Epub 2023 Oct 13.
Although pv. () has been found to be a bacterial pathogen causing bacterial leaf blight in rice for many years, the molecular mechanisms of the rice- interaction has not been fully understood. In this study, we found that XanFur of is a novel ferric uptake regulator (Fur) protein conserved among major pathogenic species. XanFur is required for the virulence of in rice, and likely involved in regulating the virulence determinants of . The expression of is induced by HO, and positively regulated by the global transcriptional regulator Clp. Our results reveal the function and regulation of the novel virulence-related Fur protein XanFur in providing new insights into the interaction mechanisms of rice-.
虽然 pv. () 多年来一直被认为是导致水稻细菌性叶斑病的细菌病原体,但水稻-相互作用的分子机制尚未完全理解。在这项研究中,我们发现 中的 XanFur 是一种新型的铁摄取调节剂(Fur)蛋白,在主要致病性 物种中保守。XanFur 是 的在水稻中的毒力所必需的,并且可能参与调节 的毒力决定因素。 的表达受 HO 诱导,并受全局转录调节剂 Clp 正向调控。我们的结果揭示了新型与毒力相关的 Fur 蛋白 XanFur 在 中的功能和调节作用,为水稻-的相互作用机制提供了新的见解。