Institut Pasteur, Université Paris Cité, Paris, France.
Eur J Immunol. 2024 Jan;54(1):e2250348. doi: 10.1002/eji.202250348. Epub 2023 Oct 20.
The importance of IL-23 and its specific receptor, IL-23R, in the pathogenesis of several chronic inflammatory diseases has been established, but the underlying pathological mechanisms are not fully understood. This review focuses on IL-23R expression and regulation in immune cells.
IL-23 及其特异性受体 IL-23R 在几种慢性炎症性疾病发病机制中的重要性已得到确立,但潜在的病理机制尚不完全清楚。本综述重点关注免疫细胞中 IL-23R 的表达和调控。