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免疫功能低下的急性白血病患儿真菌性动脉瘤的血管内治疗——病例报告及文献复习

Endovascular treatment of a mycotic aneurysm in an immunocompromised child with acute leukemia-case report and review of the literature.

作者信息

Diepenbruck Sabine Daphne, Jakob Andre, Haas Nikolaus Alexander, Mandilaras Guido

机构信息

Division of Pediatric Cardiology and Pediatric Intensive Care, University Hospital of Munich (LMU), Munich, Germany.

出版信息

Front Pediatr. 2023 Sep 28;11:1136647. doi: 10.3389/fped.2023.1136647. eCollection 2023.

Abstract

Mycotic aneurysms are dilatations of an artery, a rare but severe complication arising from infectious obliteration of the vessel wall. Thoracic aneurysms often present with unspecific symptoms and multiple diagnostic and therapeutic challenges. In an advanced state, they have an increased risk of perforation and a high mortality rate. The surgical therapeutic approach has a high perioperative complication rate. In this study, we report a case of a thoracic mycotic aortic aneurysm in an immunocompromised pediatric patient caused by bacteremia. A combination of prompt antibacterial treatment and minimally invasive stent implantation showed a good outcome, avoiding possible severe surgical problems.

摘要

真菌性动脉瘤是动脉的扩张,是一种由血管壁感染性闭塞引起的罕见但严重的并发症。胸段动脉瘤通常表现为非特异性症状,存在多种诊断和治疗挑战。在晚期,它们有穿孔风险增加和高死亡率。手术治疗方法围手术期并发症发生率高。在本研究中,我们报告了一例免疫功能低下的儿科患者因菌血症导致的胸段真菌性主动脉瘤病例。及时的抗菌治疗与微创支架植入相结合显示出良好的效果,避免了可能出现的严重手术问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23c3/10568310/cfc21f168a74/fped-11-1136647-g001.jpg

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