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环形阴茎皮肤筋膜皮瓣腹侧镶嵌式尿道成形术作为复杂长段尿道狭窄背侧镶嵌式颊黏膜移植尿道成形术的替代方法:一项回顾性研究

Circular Penile Skin Fasciocutaneous Ventral Onlay Flap Urethroplasty as an Alternative to Dorsal Onlay Buccal Mucosal Graft Urethroplasty in Complex Long-Segment Urethral Stricture: A Retrospective Study.

作者信息

Singh Rana P, Jamal Arshad

机构信息

Department of Urology, Rajendra Institute of Medical Sciences, Ranchi, IND.

出版信息

Cureus. 2023 Sep 12;15(9):e45084. doi: 10.7759/cureus.45084. eCollection 2023 Sep.

Abstract

Background A urethral stricture is the narrowing of the urethra that results in symptoms of obstruction. It can appear anywhere along the male urethra's length and has a variety of causes. The circular penile fasciocutaneous flap is employed in the successful single-stage reconstruction of long-segment complex anterior urethral strictures especially when the buccal mucosa is unavailable due to various reasons. The study has tried to identify a surgical technique that is more beneficial for the treatment of urethral strictures. Objective The objective of this research was to evaluate the outcomes of circular penile skin fasciocutaneous ventral onlay flap urethroplasty (group A) and the outcomes of dorsal onlay buccal mucosal graft urethroplasty (group B) in the management of complex long-segment penile urethral stricture. Methods In this retrospective study between December 2012 and December 2022, 60 patients with long-segment complex penile urethral stricture who underwent urethroplasty at our center were evaluated. Patients were divided into two groups according to the flap used (dorsal onlay buccal mucosal graft urethroplasty was used in 30 patients (group B), and circular penile fasciocutaneous flap (single stage) was used in 30 patients (group A)). The success rate and the mean peak flow rate were also calculated post-operation to identify the effectiveness of the surgical procedure used for urethral strictures. Results The study consisted of 60 patients in total. Group A's mean age was determined to be 51.2±16.2 years, whereas group B's mean age was determined to be 40.7±16.8 years. Preoperatively, the median urethral stricture length was 69 mm in group A (range: 20-100 mm) and 56 mm in group B (range: 30-110 mm). The intraoperative median length of the urethral stricture was 82 mm in group A (range: 20-120 mm) and 65 mm in group B (range: 40-140 mm). The mean peak flow rate was 30.9±6.8 mL/s in group A compared to 18.1±4.9 mL/s in group B. The success rate for group A was 89.7%, while the success rate for group B was 75.9%. Conclusion For complex long-segment urethral strictures, circular penile skin fasciocutaneous ventral onlay flap urethroplasty has a higher rate of success and fewer complications than dorsal onlay buccal mucosal graft urethroplasty. Along with success rate, it has a better mean peak flow rate and lower complications.

摘要

背景

尿道狭窄是指尿道变窄,导致梗阻症状。它可出现在男性尿道全长的任何部位,病因多样。环形阴茎筋膜皮瓣尤其适用于长段复杂性前尿道狭窄的一期成功重建,特别是在因各种原因无法获取颊黏膜时。本研究试图确定一种对尿道狭窄治疗更有益的手术技术。

目的

本研究的目的是评估环形阴茎皮肤筋膜皮瓣腹侧镶嵌式尿道成形术(A组)和背侧镶嵌式颊黏膜移植尿道成形术(B组)治疗复杂性长段阴茎尿道狭窄的效果。

方法

在这项回顾性研究中,对2012年12月至2022年12月期间在本中心接受尿道成形术的60例长段复杂性阴茎尿道狭窄患者进行评估。根据所使用的皮瓣将患者分为两组(30例患者采用背侧镶嵌式颊黏膜移植尿道成形术(B组),30例患者采用环形阴茎筋膜皮瓣(一期)(A组))。术后还计算成功率和平均峰值流速,以确定用于尿道狭窄的手术方法的有效性。

结果

本研究共纳入60例患者。A组平均年龄为51.2±16.2岁,而B组平均年龄为40.7±16.8岁。术前,A组尿道狭窄的中位长度为69mm(范围:20 - 100mm),B组为56mm(范围:30 - 110mm)。术中A组尿道狭窄的中位长度为82mm(范围:20 - 120mm),B组为65mm(范围:40 - 140mm)。A组平均峰值流速为30.9±6.8mL/s,而B组为18.1±4.9mL/s。A组成功率为89.7%,而B组成功率为75.9%。

结论

对于复杂性长段尿道狭窄,环形阴茎皮肤筋膜皮瓣腹侧镶嵌式尿道成形术比背侧镶嵌式颊黏膜移植尿道成形术成功率更高,并发症更少。除成功率外,其平均峰值流速更好,并发症更低。

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