Hospital El Cruce Ringgold standard institution - Neurology, Buenos Aires, Argentina.
CONICET La Plata Ringgold standard institution - Studies in Neuroscience and Complex Systems (ENyS), Buenos Aires, Argentina.
Epileptic Disord. 2024 Feb;26(1):126-132. doi: 10.1002/epd2.20172. Epub 2023 Oct 28.
Ictal semiology is essential to identify the epileptogenic zone (EZ), especially in drug-resistant focal epilepsy (DRE), as its accurate identification determines the surgical prognosis. Dancing is highly unusual ictal semiology, and its underlying neural networks remain somehow unclear since both temporal and frontal lobe (FL) have been implicated in its generation. We present a 21-year-old male with DRE characterized by dancing seizures. Homemade videos were obtained. Through a non-invasive pre-surgical evaluation, the epileptogenic zone was localized within a gross lesion in the left FL. Using stereo electroencephalography (SEEG), we successfully identified the ictal-onset zone in the mesial middle, inferior, and orbito-frontal cortex, with rapid propagation of ictal activity extending backward and laterally to the precentral regions. Subsequently, a left frontal middle and inferior gyrectomy was performed, resulting in seizure freedom for the patient. Pathology results revealed a mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE). Atypical seizure semiology, such as dancing, provides an interesting starting point for the analysis of the areas involved in the EZ. Further intracranial recordings are required to fully comprehend the underlying networks and interactions of cerebral areas during dancing seizures.
发作半侧体征对于确定致痫区(EZ)至关重要,尤其是在耐药性局灶性癫痫(DRE)中,因为其准确识别决定了手术预后。舞蹈样发作是一种非常罕见的发作半侧体征,其潜在的神经网络仍然有些不清楚,因为颞叶和额叶(FL)都与它的产生有关。我们报告了一例 21 岁男性的 DRE,表现为舞蹈样发作。获得了自制视频。通过非侵入性术前评估,将致痫区定位于左侧 FL 内的一个大体病变内。使用立体脑电图(SEEG),我们成功地确定了内侧中部、下部和眶额皮质的发作起始区,发作活动迅速向后和向外侧扩展到中央前区。随后进行了左侧额叶中部和下部脑回切除术,使患者无癫痫发作。病理结果显示轻度皮质发育畸形伴少突胶质细胞增生(MOGHE)。不典型的发作半侧体征,如舞蹈样发作,为分析 EZ 所涉及的区域提供了一个有趣的起点。需要进一步的颅内记录来充分理解舞蹈样发作期间大脑区域的潜在网络和相互作用。