Department of Trauma and Emergency Surgery, Chang Gung Memorial Hospital, Linkou Branch, Chang Gung University, Taoyuan, Taiwan.
Department of General Surgery, Chang Gung Memorial Hospital, Keelung Branch, Chang Gung University, Keelung, Taiwan.
World J Surg. 2023 Dec;47(12):3116-3123. doi: 10.1007/s00268-023-07224-w. Epub 2023 Oct 18.
This study aimed to validate the previously reported association between delayed bladder repair and increased infection rates using the National Trauma Data Bank (NTDB).
Bladder injury patients with bladder repair in the NTDB from 2013 to 2015 were included. Propensity score matching (PSM) was used to compare mortality, infection rates, and hospital length of stay (LOS) between patients who underwent bladder repair within 24 h and those who underwent repair after 24 h. Linear regression and multivariate logistic regression analyses were also performed.
A total of 1658 patients were included in the study. Patients who underwent bladder repair after 24 h had significantly higher infection rates (5.4% vs. 1.2%, p = 0.032) and longer hospital LOS (17.1 vs. 14.0 days, p = 0.032) compared to those who underwent repair within 24 h after a well-balanced 1:1 PSM (N = 166). Linear regression analysis showed a positive correlation between time to bladder repair and hospital LOS for patients who underwent repair after 24 h (B-value = 0.093, p = 0.034). Multivariate logistic regression analysis indicated that bladder repair after 24 h increased the risk of infection (odds = 3.162, p = 0.018). Subset analyses were performed on patients who underwent bladder repairs within 24 h and were used as a control group. These analyses showed that the time to bladder repair did not significantly worsen outcomes.
Delayed bladder repair beyond 24 h increases the risk of infection and prolongs hospital stays. Timely diagnosis and surgical intervention remain crucial for minimizing complications in bladder injury patients.
本研究旨在利用国家创伤数据库(NTDB)验证先前报道的延迟性膀胱修复与感染率增加之间的关联。
纳入 NTDB 中 2013 年至 2015 年接受膀胱修复的膀胱损伤患者。采用倾向评分匹配(PSM)比较 24 小时内接受膀胱修复和 24 小时后接受修复的患者的死亡率、感染率和住院时间(LOS)。还进行了线性回归和多变量逻辑回归分析。
共纳入 1658 例患者。与 24 小时内接受修复的患者相比,24 小时后接受修复的患者感染率(5.4% vs. 1.2%,p = 0.032)和住院 LOS(17.1 天 vs. 14.0 天,p = 0.032)显著更高。经过均衡的 1:1 PSM(N = 166)后,差异有统计学意义。线性回归分析显示,对于 24 小时后接受修复的患者,膀胱修复时间与住院 LOS 呈正相关(B 值=0.093,p = 0.034)。多变量逻辑回归分析表明,24 小时后进行膀胱修复会增加感染的风险(比值比=3.162,p = 0.018)。对 24 小时内接受膀胱修复的患者进行亚组分析,并将其作为对照组。这些分析表明,膀胱修复时间不会显著恶化结果。
超过 24 小时的延迟性膀胱修复会增加感染风险并延长住院时间。及时诊断和手术干预仍然是减少膀胱损伤患者并发症的关键。