Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.
Curr Cardiol Rep. 2023 Oct;25(10):1233-1246. doi: 10.1007/s11886-023-01948-w. Epub 2023 Oct 18.
Anomalous aortic origin of a coronary artery (AAOCA) is a rare congenital coronary anomaly with the potential to cause myocardial ischemia and adverse cardiac events. The presence of AAOCA anatomy itself does not necessarily implicate a need for revascularization. Therefore, the purpose of this review is to assess how noninvasive comprehensive anatomic- and physiologic evaluation may guide patient management.
The assessment of AAOCA includes an accurate description of the anomalous origin/vessel course including anatomical high-risk features such as a slit-like ostium, proximal narrowing, elliptic vessel shape, acute take-off angle, intramural course, and possible concomitant coronary atherosclerosis and hemodynamics. Various cardiac imaging modalities offer unique advantages and capabilities in visualizing these anatomical and functional aspects of AAOCA. This review explored the role of noninvasive multimodality imaging in the characterization of AAOCA by highlighting the strengths, limitations, and potential applications of the current different cardiac imaging methods, with a focus on the pathophysiology of myocardial ischemia and stress testing protocols.
冠状动脉异常起源(AAOCA)是一种罕见的先天性冠状动脉异常,可能导致心肌缺血和不良心脏事件。AAOCA 解剖结构的存在本身并不一定需要血运重建。因此,本综述的目的是评估无创综合解剖和生理评估如何指导患者管理。
AAOCA 的评估包括对异常起源/血管路径的准确描述,包括解剖学高危特征,如裂隙样开口、近端狭窄、椭圆形血管形状、锐角起始、壁内路径以及可能的伴随冠状动脉粥样硬化和血液动力学。各种心脏成像方式在可视化 AAOCA 的这些解剖和功能方面具有独特的优势和能力。本综述探讨了非侵入性多模态成像在 AAOCA 特征描述中的作用,强调了当前不同心脏成像方法的优缺点和潜在应用,重点关注心肌缺血的病理生理学和应激测试方案。