Suppr超能文献

AGouTI-基因组和转录组区间的灵活注释。

AGouTI-Flexible Annotation of Genomic and Transcriptomic Intervals.

机构信息

Department of Computational Biology, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University in Poznań, Poznań, Poland.

出版信息

PLoS Comput Biol. 2023 Oct 18;19(10):e1011527. doi: 10.1371/journal.pcbi.1011527. eCollection 2023 Oct.

Abstract

The recent development of high-throughput workflows in genomics and transcriptomics revealed that efficient annotation of such results is essential for researchers to draw conclusions from obtained results. Although some tools are available, their functionality is limited. Here, we present AGouTI-a universal tool for flexible annotation of any genomic or transcriptomic coordinates using known genomic features deposited in different publicly available databases in the form of GTF or GFF files. In contrast to currently available tools, AGouTI is designed to provide a flexible selection of genomic features overlapping or adjacent to annotated intervals and can be used on custom column-based text files obtained from different data analysis pipelines. Although providing many unique options, AGouTI is straightforward in installation and usage, enabling effortless integration into existing data analysis workflows.

摘要

近年来基因组学和转录组学中高通量工作流程的发展表明,对这些结果进行高效注释对于研究人员从获得的结果中得出结论至关重要。尽管有一些工具可用,但它们的功能有限。在这里,我们介绍了 AGouTI,这是一种通用工具,可使用以 GTF 或 GFF 文件形式存储在不同公开可用数据库中的已知基因组特征,灵活注释任何基因组或转录组坐标。与现有的工具不同,AGouTI 旨在提供对注释区间重叠或相邻的基因组特征的灵活选择,并且可以在从不同数据分析管道获得的基于自定义列的文本文件上使用。尽管提供了许多独特的选项,但 AGouTI 在安装和使用方面非常简单,能够轻松集成到现有的数据分析工作流程中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3468/10621952/a1ff69e77e21/pcbi.1011527.g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验