Department of Medical Cosmetology and Plastic Surgery, The Third People's Hospital of Chengdu, Chengdu, China.
Department of Maxillofacial Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
J Craniomaxillofac Surg. 2023 Nov;51(11):675-681. doi: 10.1016/j.jcms.2023.10.001. Epub 2023 Oct 6.
The aim of this study was to investigate the characteristics of condylar resorption in craniofacial microsomia (CFM) patients following mandibular distraction osteogenesis (MDO). Patients with unilateral type-IIa and type-IIb CFM, who had completed MDO and mandibular distractor extraction (MDE), were recruited. The height and volume of the condyle were measured on three-dimension models created by the analysis of computed tomography (CT) data. Normality analysis was performed using the Shapiro-Wilk test. Data for the affected and unaffected sides were compared using the paired t-test or Wilcoxon signed-rank test. Data for both type-IIa and type-IIb CFM were compared using the independent-samples t-test or Mann-Whitney U test. The Pearson or Spearman correlation was used to determine the correlations of condylar resorption rate with related measurements. In total, 48 type-IIa and 48 type-IIb CFM patients were included. The condylar resorption rate in type-IIa CFM (0.35 ± 0.32) was significantly associated with the height of the condyle (r = 0.776, p < 0.001) and distraction distance (r = 0.447, p = 0.001), while the condylar resorption rate in type-IIb CFM (0.49 ± 0.46) was significantly associated with the height of the condyle (r = 0.924, p < 0.001). However, there was no significant difference in condylar resorption rate between type-IIa and type-IIb CFM (p = 0.075). In addition to occlusal changes, no other negative symptoms of the TMJ were observed with condylar resorption. Condylar resorption was evident in CFM patients following mandibular distraction osteogenesis, and the condylar resorption rate showed a relationship with distraction distance and condylar height.
本研究旨在探讨颅面骨发育不全（CFM）患者下颌骨牵引成骨（MDO）后髁突吸收的特点。招募了单侧 IIa 型和 IIb 型 CFM 患者，这些患者已完成 MDO 和下颌骨牵引器取出（MDE）。通过对 CT 数据的分析，在三维模型上测量髁突的高度和体积。使用 Shapiro-Wilk 检验进行正态性分析。使用配对 t 检验或 Wilcoxon 符号秩检验比较患侧和健侧的数据。使用独立样本 t 检验或 Mann-Whitney U 检验比较 IIa 型和 IIb 型 CFM 之间的数据。使用 Pearson 或 Spearman 相关系数确定髁突吸收率与相关测量值的相关性。共纳入 48 例 IIa 型和 48 例 IIb 型 CFM 患者。IIa 型 CFM 的髁突吸收率（0.35±0.32）与髁突高度（r=0.776，p<0.001）和牵引距离（r=0.447，p=0.001）显著相关，而 IIb 型 CFM 的髁突吸收率（0.49±0.46）与髁突高度（r=0.924，p<0.001）显著相关。然而，IIa 型和 IIb 型 CFM 之间的髁突吸收率无显著差异（p=0.075）。除了咬合变化外，髁突吸收后未观察到 TMJ 的其他负面症状。下颌骨牵引成骨后 CFM 患者髁突吸收明显，髁突吸收率与牵引距离和髁突高度有关。
