Wei Ruoqu, Liu Haifei, Zhang Zhen, Chen Fuying, Chen Jiawen, Xu Qianyue, Yu Hong, Liang Jianying, Yao Zhirong
Department of Dermatology, Xinhua Hospital, Shanghai, China.
Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Ann Dermatol. 2023 May;35(Suppl 1):S79-S83. doi: 10.5021/ad.20.310.
Subcutaneous panniculitis-like T-cell lymphoma (SPTL) is an extremely rare, indolent skin malignancy that can be difficult to distinguish from autoimmune disease-associated panniculitides. Here, we describe a 12-year-old boy who was diagnosed at age 7 years with dermatomyositis with classical manifestations, including poikiloderma, Gottron's sign, and symmetric muscle weakness. Recently, the boy presented multiple subcutaneous nodules and fever. Histopathological examination and immunohistochemical staining revealed coexistence of SPTL. To our knowledge, this is the first case of dermatomyositis accompanied with SPTL. This case alert clinical physicians of the possibility of SPTL should be considered when a patient with dermatomyositis has new lesions presenting as nodules and unknown fever.
皮下脂膜炎样T细胞淋巴瘤（SPTL）是一种极其罕见的惰性皮肤恶性肿瘤，可能难以与自身免疫性疾病相关的脂膜炎相区分。在此，我们描述一名12岁男孩，他在7岁时被诊断为具有典型表现的皮肌炎，包括皮肤异色症、Gottron征和对称性肌无力。最近，该男孩出现多个皮下结节和发热。组织病理学检查和免疫组化染色显示存在SPTL。据我们所知，这是首例伴有SPTL的皮肌炎病例。该病例提醒临床医生，当皮肌炎患者出现表现为结节的新病变和不明原因发热时，应考虑SPTL的可能性。
