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心脏移植术后早期纵隔炎患者因乳头肌破裂导致严重三尖瓣反流的处理

Management of severe tricuspid valve regurgitation due to ruptured papillary muscle in a patient with mediastinitis early after heart transplant.

作者信息

Schumer Erin M, Kotkar Kunal D, Masood M Faraz, Kaneko Tsuyoshi, Damiano Ralph J, Pawale Amit

机构信息

Division of Cardiothoracic Surgery, Washington University, St Louis, Mo.

出版信息

JTCVS Tech. 2023 Jul 26;21:106-108. doi: 10.1016/j.xjtc.2023.07.014. eCollection 2023 Oct.

Abstract

OBJECTIVE

Even though severe tricuspid regurgitation is not uncommon after cardiac transplantation, primary severe tricuspid regurgitation is rare. We present such a case with additional complexities.

METHODS

The patient was 44-year-old man with a HeartWare durable left ventricular assist device (Heartware Inc) who received a temporary right ventricular assist device (RVAD) with a ProtekDuo cannula (LivaNova Inc USA) for refractory ventricular fibrillation and underwent a heart transplant as United Network for Organ Sharing Status 1, in the presence of partially compensated cardiogenic shock, renal failure. Given complex re-operative surgery in a volume-overloaded patient with unknown pulmonary vascular resistance, an RVAD cannula was preserved and re- inserted during cardiac transplant. Postoperatively he required hemodialysis, had severe primary tricuspid regurgitation discovered after RVAD removal and developed Enterobacter mediastinitis. He underwent complex tricuspid valve repair for flail tricuspid leaflet due to ruptured papillary muscle likely due to RVAD cannula injury, after multiple mediastinal washouts and was followed by delayed chest reconstruction.

RESULTS

The patient is doing well, 6 months after discharge to home, asymptomatic, without re-admissions, on renal recovery path, with no tricuspid regurgitation and good biventricular function.

CONCLUSIONS

Replacing the tricuspid valve in presence of hemodialysis catheter, immunosuppression and mediastinitis could be high risk for endocarditis. Even though we have short-term follow-up, tricuspid valve repair can be an effective way of managing primary severe regurgitation especially when there is a desire or need to avoid valve replacement.

摘要

目的

尽管心脏移植后严重三尖瓣反流并不罕见,但原发性严重三尖瓣反流却很少见。我们报告了这样一例伴有其他复杂情况的病例。

方法

该患者为一名44岁男性,植入了HeartWare耐用型左心室辅助装置(Heartware公司),因难治性室颤接受了带有ProtekDuo套管(美国LivaNova公司)的临时右心室辅助装置(RVAD),并在存在部分代偿性心源性休克、肾衰竭的情况下,作为器官共享联合网络1级状态接受了心脏移植。鉴于在一名肺血管阻力未知且容量超负荷的患者中进行复杂的再次手术,RVAD套管在心脏移植期间被保留并重新插入。术后他需要进行血液透析,在移除RVAD后发现有严重的原发性三尖瓣反流,并发生了产气肠杆菌纵隔炎。在多次纵隔冲洗后,他因乳头肌破裂导致连枷状三尖瓣叶,可能是由于RVAD套管损伤,接受了复杂的三尖瓣修复,随后进行了延迟的胸部重建。

结果

患者出院回家6个月后情况良好,无症状,未再次入院,肾功能正在恢复,无三尖瓣反流,双心室功能良好。

结论

在存在血液透析导管、免疫抑制和纵隔炎的情况下更换三尖瓣可能会有较高的心内膜炎风险。尽管我们的随访时间较短,但三尖瓣修复可能是治疗原发性严重反流的有效方法,尤其是当希望或需要避免瓣膜置换时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1d3/10580097/09e3ecac9663/fx1.jpg

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