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种植体支持的严重萎缩上颌骨修复的临床结果:系统评价。

Clinical outcomes of implant-supported prosthetic rehabilitation of severely atrophic maxilla: A systematic review.

机构信息

Department of Prosthodontics, VSPM DCRC, Nagpur, Maharashtra, India.

出版信息

J Indian Prosthodont Soc. 2023 Oct-Dec;23(4):335-346. doi: 10.4103/jips.jips_360_23.

Abstract

AIM

The purpose of this systematic review is to evaluate the clinical outcomes for the various methods of rehabilitation of a severely atrophic maxilla with the help of implant-supported fixed prosthesis.

MATERIALS AND METHODS

The relevant publications published between 2013 and 2022 and written only in English were identified using an electronic search. The primary research question for this study was developed based on the PICO framework, which stands for population, intervention, control, and outcomes which was "What are the clinical outcomes of implant-supported prosthetic rehabilitation in patients with severely atrophic maxilla?" The relevancy of the articles was confirmed by examining their titles, abstracts, and complete texts to determine whether they satisfied the requirements for inclusion. Utilizing specialized study design-related bias assessment forms, the risk of bias was evaluated.

RESULTS

The database search resulted in 1568 results; however, 1529 of them were eliminated because of insufficient, duplicate, or missing data. Additionally, manual searching yielded 11 articles. After 50 full-text papers were assessed for eligibility, 17 articles were eliminated. Thus, 33 studies in total are included in the current systematic review. Risk of bias analysis and GRADE evidence analysis were performed. Data were found to be heterogeneous and thus meta-analysis could not be done and narrative synthesis is presented.

CONCLUSION

The patient's condition and the clinician's expertise play a role in taking the decision on choice of technique for the fixed implant-supported rehabilitation of the severely atrophic maxilla. A high success and survival rate is produced by the majority of fixed implant-assisted prostheses despite the biologic and prosthetic problems. A single approach cannot be recommended as the gold standard. The choice is dependent on the patient's biological factors as well as the clinician's expertise. The included studies were assessed using GRADE criteria. The quality of evidence is low-medium. Therefore, to better comprehend the clinical effectiveness of the treatment alternatives, more well-designed randomized controlled trials with longer follow-up period are required.

摘要

目的

本系统评价的目的是评估在种植体支持的固定修复帮助下,对严重萎缩上颌进行各种康复方法的临床效果。

材料与方法

通过电子搜索,确定了 2013 年至 2022 年间发表的仅用英文撰写的相关出版物。本研究的主要研究问题基于 PICO 框架制定,即人群、干预、对照和结果,其问题是“在严重萎缩上颌患者中,种植体支持的修复体康复的临床效果如何?”通过检查文章的标题、摘要和全文来确认文章的相关性,以确定它们是否符合纳入要求。利用专门的研究设计相关偏倚评估表格来评估偏倚风险。

结果

数据库搜索产生了 1568 个结果,但由于数据不足、重复或缺失,其中 1529 个结果被排除。此外,通过手动搜索得到了 11 篇文章。在评估了 50 篇全文论文的合格性后,又排除了 17 篇。因此,目前的系统评价共包括 33 项研究。进行了风险偏倚分析和 GRADE 证据分析。发现数据存在异质性,因此无法进行荟萃分析,仅呈现叙述性综合。

结论

患者的病情和临床医生的专业知识在决定严重萎缩上颌的固定种植体支持修复技术方面发挥作用。尽管存在生物学和修复学问题,但大多数固定种植体辅助修复体都能产生较高的成功率和存活率。不能推荐单一方法作为金标准。选择取决于患者的生物学因素以及临床医生的专业知识。纳入的研究使用 GRADE 标准进行评估。证据质量为低-中。因此,需要更多设计良好的、具有更长随访期的随机对照试验,以更好地了解治疗选择的临床效果。

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