Powell Eleanor A, Hata D Jane, Starolis Meghan W
Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, 234 Goodman St., Cincinnati, OH 45219, United States.
Department of Laboratory Medicine and Pathology, Mayo Clinic Florida, 4500 San Pablo Rd., Jacksonville, FL 32266, United States.
J Clin Virol. 2023 Dec;169:105612. doi: 10.1016/j.jcv.2023.105612. Epub 2023 Oct 15.
Diagnosis of gastrointestinal infections has been revolutionized by the development of in vitro diagnostic (IVD) multiplex molecular panels for the detection of viral nucleic acids. In addition to a high degree of accuracy, these panels are commercially available and relatively simple to perform in the clinical laboratory. However, use of these panels must be carefully considered owing to the laboratory costs of the test, limited reimbursement, and potential for overuse. In this review from the Pan American Society for Clinical Virology, we focus on the viral components of GI multiplex panels (GIPs), presenting a brief overview of pathogens included on most panels and a discussion of advantages and challenges of the inclusion of viral targets on GIPs that should be considered before implementation in the clinical laboratory.
用于检测病毒核酸的体外诊断（IVD）多重分子检测板的开发彻底改变了胃肠道感染的诊断方式。除了高度准确外，这些检测板在临床上可买到，且在临床实验室操作相对简单。然而，由于检测的实验室成本、报销有限以及存在过度使用的可能性，必须谨慎考虑使用这些检测板。在泛美临床病毒学会的这篇综述中，我们重点关注胃肠道多重检测板（GIPs）的病毒成分，简要概述大多数检测板所包含的病原体，并讨论在临床实验室实施前应考虑的将病毒靶点纳入GIPs的优点和挑战。
