Erciyes University Faculty of Medicine, Department of Ophthalmology, Kayseri, Türkiye.
Elbistan State Hospital, Clinic of Ophthalmology, Kahramanmaraş, Türkiye.
Turk J Ophthalmol. 2023 Oct 19;53(5):289-293. doi: 10.4274/tjo.galenos.2023.37622.
The primary objective of this study was to evaluate the agreement of visual acuity (VA) obtained with the sweep visual evoked potential (sVEP) method with the VA obtained with the Snellen chart. The secondary objective was to examine the effect of age and gender on agreement.
Best corrected VAs of subjects were recorded with the Snellen chart, and sVEP testing was performed according to the recommendations of the International Society for Clinical Electrophysiology of Vision (ISCEV). Snellen VAs and sVEP measurements were analyzed using logMAR conversion for statistical analysis. Agreement was evaluated with Bland-Altman analysis.
The study included 49 subjects with a mean age of 53.5±17.3 years (range: 19-75 years) and mean Snellen VA of 0.31±0.32 logMAR (range: 1.3-0.0 logMAR). In the Bland-Altman analysis, the mean differences between the VA and sVEP measurements (VA-sVEP) were significantly different and outside the limits of agreement (p=0.035). A significant proportional bias (p=0.0007) was found in the regression analysis performed between VA-sVEP and the mean VA. According to the Bland-Altman analysis of sex subgroups, there was a significant difference between VA and sVEP measurements in female subjects (p=0.006). The difference between VA and sVEP measurement increased significantly with older age (R: 0.306, p<0.001, β: 0.05 [0.03, 0.08]).
In conclusion, sVEP measurements and VAs did not show statistical agreement. Cranial anatomy and endocrine differences of the subjects may affect their sVEP measurements. The difference between the methods varies according to VA level. Directly using sVEP results instead of VA would not be appropriate.
本研究的主要目的是评估扫频视觉诱发电位（sVEP）法获得的视力（VA）与 Snellen 图表获得的 VA 的一致性。次要目的是检查年龄和性别对一致性的影响。
使用 Snellen 图表记录受试者的最佳矫正视力（VA），并根据国际临床视觉电生理学学会（ISCEV）的建议进行 sVEP 测试。使用对数最小分辨角对数（logMAR）转换对 Snellen VA 和 sVEP 测量值进行分析，以便进行统计分析。使用 Bland-Altman 分析评估一致性。
该研究纳入了 49 名受试者，平均年龄为 53.5±17.3 岁（范围：19-75 岁），平均 Snellen VA 为 0.31±0.32 logMAR（范围：1.3-0.0 logMAR）。在 Bland-Altman 分析中，VA 和 sVEP 测量值（VA-sVEP）之间的平均差异显著且超出了一致性范围（p=0.035）。在 VA-sVEP 与平均 VA 之间进行的回归分析中发现了显著的比例偏差（p=0.0007）。根据性别亚组的 Bland-Altman 分析，女性受试者的 VA 和 sVEP 测量值之间存在显著差异（p=0.006）。随着年龄的增长，VA 和 sVEP 测量值之间的差异显著增加（R：0.306，p<0.001，β：0.05 [0.03，0.08]）。
总之，sVEP 测量值和 VA 之间没有显示出统计学上的一致性。受试者的颅面解剖和内分泌差异可能会影响他们的 sVEP 测量值。两种方法之间的差异因 VA 水平而异。直接使用 sVEP 结果而不是 VA 是不合适的。
