Case Western Reserve University School of Medicine, Cleveland, Ohio.
Department of Orthopedic Surgery, Hospital for Special Surgery, New York, New York.
J Arthroplasty. 2024 Apr;39(4):1083-1087.e1. doi: 10.1016/j.arth.2023.10.037. Epub 2023 Oct 21.
Periprosthetic femur fracture (PFF) following total hip arthroplasty (THA) is a leading cause of early reoperation. The objective of this study was to compare rates of periprosthetic joint infection (PJI) and reoperation following PFFs occurring early postoperatively to those that occurred late.
We retrospectively identified 173 consecutive surgically managed PFFs following primary THA. Cases were categorized as "early" if they occurred within 90 days of THA (n = 117) or "late" if they occurred following the initial 90 days (n = 56). Mean age at time of PFF was 68 years (range, 26 to 96) and 60% were women. Mean body mass index was 29 (range, 16 to 52). Mean follow-up was 2 years (range, 0 to 13). Kaplan-Meier survival analysis estimated cumulative incidences of PJI and reoperation.
Early PFFs had higher 2-year cumulative incidence of PJI (11% versus 0%, P < .001) and reoperation (24% versus 13%, P = .110). Following early PFF, 27 patients required reoperation (ie, 13 for PJI, 5 for instability, 2 for re-fracture, 2 for painful hardware, 2 for non-union, 1 for adverse local tissue reaction, 1 for aseptic loosening, and 1 for leg-length discrepancy). Following late PFF, 5 patients required reoperation (ie, 3 for instability, 1 for re-fracture, and 1 for non-union).
There are greater incidences of PJIs and overall reoperations following early PFFs compared to late PFFs after THA. In addition to focusing efforts on prevention of early PFFs, surgeons should consider antiseptic interventions to mitigate the increased risk of PJI after treatment of early PFF.
全髋关节置换术后(THA)发生的股骨假体周围骨折(PFF)是早期再次手术的主要原因。本研究的目的是比较术后早期和晚期发生的 PFF 后假体周围关节感染(PJI)和再次手术的发生率。
我们回顾性地确定了 173 例经手术治疗的初次 THA 后连续发生的 PFF。如果发生在初次 THA 后 90 天内(n=117),则病例分类为“早期”;如果发生在初次 90 天后,则病例分类为“晚期”(n=56)。PFF 时的平均年龄为 68 岁(范围,26 岁至 96 岁),60%为女性。平均体重指数为 29(范围,16 至 52)。平均随访时间为 2 年(范围,0 至 13 年)。Kaplan-Meier 生存分析估计 PJI 和再次手术的累积发生率。
早期 PFF 的 2 年 PJI 累积发生率较高(11%比 0%,P<0.001)和再次手术(24%比 13%,P=0.110)。在早期 PFF 后,27 例患者需要再次手术(即 13 例 PJI,5 例不稳定,2 例再骨折,2 例疼痛性硬件,2 例不愈合,1 例局部组织不良反应,1 例无菌性松动,1 例肢体长度差异)。在晚期 PFF 后,5 例患者需要再次手术(即,3 例不稳定,1 例再骨折,1 例不愈合)。
与 THA 后晚期 PFF 相比,早期 PFF 后 PJI 和总体再次手术的发生率更高。除了专注于预防早期 PFF 外,外科医生还应考虑使用抗菌干预措施来减轻治疗早期 PFF 后 PJI 的风险增加。