增强计算机断层扫描及氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描在胃大B细胞淋巴瘤后发生的罕见小肠组织细胞肉瘤中的应用

Enhanced Computed Tomography and F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Uncommon Histiocytic Sarcoma of Small Intestine Arising after Gastric Large B-Cell Lymphoma.

作者信息

Cheon Miju, Yoo Jang, Kim Hae Su, Lee Miji

机构信息

Department of Nuclear Medicine, Veterans Health Service Medical Center, Seoul 05368, Republic of Korea.

Division of Hematology-Oncology, Department of Internal Medicine, Veterans Health Service Medical Center, Seoul 05368, Republic of Korea.

出版信息

Diagnostics (Basel). 2023 Oct 12;13(20):3189. doi: 10.3390/diagnostics13203189.

DOI:10.3390/diagnostics13203189

PMID:37892010

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10606069/

Abstract

Histiocytic sarcoma (HS) is an extremely rare and aggressive malignant neoplasm of hematopoietic origin that shows morphologic and immunophenotypic evidence of histiocytic differentiation. In approximately 25% of the cases, presumed transdifferentiation of a preexisting hematolymphoid disorder can be demonstrated. Various extranodal sites, particularly the gastrointestinal tract, soft tissue, skin, and spleen, can be involved. Enhanced CT and FDG PET/CT findings of extranodal histiocytic sarcoma have been barely reported. We present a case with extranodal HS originating in the small intestine after gastric large B-cell lymphoma, mistaken for prostate cancer metastasis in a 76-year-old man.

摘要

组织细胞肉瘤（HS）是一种极为罕见且具有侵袭性的造血源性恶性肿瘤，其具有组织细胞分化的形态学和免疫表型证据。在大约25%的病例中，可以证实存在先前血液淋巴系统疾病的假定转分化。各种结外部位均可受累，尤其是胃肠道、软组织、皮肤和脾脏。关于结外组织细胞肉瘤的增强CT和FDG PET/CT表现鲜有报道。我们报告一例76岁男性患者，其在胃大B细胞淋巴瘤后发生起源于小肠的结外HS，最初被误诊为前列腺癌转移。