Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Community Research Program, Faculty of Medicine, Universitas Pembangunan Nasional Veteran Jakarta, Indonesia.
Diabetes Metab Syndr. 2023 Nov;17(11):102878. doi: 10.1016/j.dsx.2023.102878. Epub 2023 Oct 20.
Female sexual dysfunction (FSD) is a neglected chronic complication of diabetes. However, there is a scarcity of data in Indonesia, which is currently ranked as the 5th in the world for the number of people with Type 2 Diabetes (T2D). Our study aims to analyze the prevalence and factors of FSD among T2D patients in Indonesia.
Literature searching was performed in PubMed/Medline®, CINAHL®, Embase®, Proquest®, Scopus®, local journals and libraries. All studies in searching keywords "sexual", "diabetes" and "Indonesia" with Medical Subject Headings (MeSH) terms were included, without time or language restriction. Pooled prevalence and odds ratio of associated factors of FSD were analyzed using STATA.
Ten studies comprised 572 females with T2D were included in this review. The pooled prevalence of FSD reached 52% (95% CI = 0.49-0.56; I 93.9%, p < 0.001). After removing one study that was conducted with an unstandardized questionnaire cut-off value, the pooled prevalence of FSD was 62% (95% CI = 0.58-0.66; I 68.7%, p = 0.001). Age more than 45 years old and or menopause, and the use of antihypertensives were associated with FSD. While Hemoglobin A1c (HbA1c) is only correlated with a desire for sexual dysfunction.
FSD was prevalent among T2D patients in Indonesia and was associated with age more than 45 years old, menopause, and the use of antihypertensive medications.
女性性功能障碍（FSD）是糖尿病的一种被忽视的慢性并发症。然而，印度尼西亚的数据却很少，目前印度尼西亚的 2 型糖尿病（T2D）患者人数在全球排名第 5。我们的研究旨在分析印度尼西亚 T2D 患者中 FSD 的患病率和相关因素。
在 PubMed/Medline®、CINAHL®、Embase®、Proquest®、Scopus®、当地期刊和图书馆中进行文献检索。所有研究均使用医学主题词（MeSH）术语搜索关键字“性”、“糖尿病”和“印度尼西亚”，无时间或语言限制。使用 STATA 分析 FSD 相关因素的合并患病率和优势比。
本综述共纳入了 10 项研究，包含 572 名 T2D 女性患者。FSD 的总患病率为 52%（95%CI=0.49-0.56；I 93.9%，p<0.001）。在剔除一项采用非标准化问卷截断值的研究后，FSD 的总患病率为 62%（95%CI=0.58-0.66；I 68.7%，p=0.001）。年龄超过 45 岁和/或绝经，以及使用抗高血压药物与 FSD 相关。而糖化血红蛋白（HbA1c）仅与性欲障碍相关。
印度尼西亚 T2D 患者中 FSD 较为普遍，与年龄超过 45 岁、绝经和使用抗高血压药物有关。
