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真实世界中印度家庭血压监测数据的地理和社会经济学分布(GRAND 研究):在印度 18 家医疗中心进行的观察性研究方案。

GeogRaphic and socioecoNomic Distribution of real-world Indian data of home blood pressure monitoring (GRAND Study): Study protocol for an observational study in 18 medical centers across India.

机构信息

Department of Physiology, Officiating Head Department of Family Medicine, King George's Medical University, Lucknow, India.

Global Medical Affairs, Asia Pacific Regional, Omron Healthcare Singapore, Pte. Ltd., Alexandra TechnoPark, Singapore.

出版信息

J Clin Hypertens (Greenwich). 2023 Dec;25(12):1105-1134. doi: 10.1111/jch.14713. Epub 2023 Nov 1.

Abstract

One-fourth of death in India is attributed to cardiovascular disease (CVD) and more than 80% is related to ischemic heart disease and stroke. The main risk factor for CVD is hypertension. Every third person in India suffers from hypertension and the prevalence increased drastically in the past 20 years, especially among the youngest age group of 20 and 44 years. Regardless of being under anti-hypertension medication, the blood pressure (BP) control rate in the country is still low ranging between 6% and 28% only. Assessing the "true BP control rate" should be performed using both clinic BP measurement and out-of-office BP measurement as the latter shows better prognosis for patients' hypertension and CVD outcomes. Home blood pressure monitoring (HBPM) shows superiority over ambulatory BP measurement as multiple measurements can be collected at the patient's convenience. Only limited evidence on HBPM in India is available and it's either lacking in hypertension participants or of a small sample size. This study will investigate the real BP control status among 2000 hypertensive patients from 18 centers in 12 states across Pan-India. The outcome of this study will emphasize the value of establishing BP control management practice guidelines suitable for physicians and help policymakers in building proper strategies for hypertension management to reduce the CVD burden on the health situation in India.

摘要

印度四分之一的死亡归因于心血管疾病(CVD),其中超过 80%与缺血性心脏病和中风有关。CVD 的主要风险因素是高血压。印度每三个人中就有一人患有高血压,在过去的 20 年中,这种患病率急剧上升,尤其是在 20 至 44 岁的最年轻年龄组中。尽管印度有三分之一的人正在接受抗高血压药物治疗,但该国的血压(BP)控制率仍然很低,仅为 6%至 28%。评估“真正的 BP 控制率”应该同时使用诊室血压测量和非诊室血压测量,因为后者可以更好地预测患者的高血压和 CVD 结局。家庭血压监测(HBPM)优于动态血压测量,因为可以在患者方便的时候多次采集测量值。印度仅有有限的 HBPM 证据,要么缺乏高血压参与者,要么样本量较小。这项研究将在印度 12 个邦的 18 个中心调查 2000 名高血压患者的真实 BP 控制状况。该研究的结果将强调为医生制定适合的 BP 控制管理实践指南的价值,并帮助决策者制定适当的高血压管理策略,以减轻 CVD 对印度卫生状况的负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b48/10710551/d7bcf8a39838/JCH-25-1105-g019.jpg

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