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肥胖儿童距离成为慢性病成年患者还有多远?

How close are children with obesity to becoming an adult with chronic illnesses?

机构信息

Department of Public Health, Ondokuz Mayıs University - Faculty of Medicine, Samsun, Turkey.

出版信息

Chronic Illn. 2024 Sep;20(3):535-544. doi: 10.1177/17423953231213847. Epub 2023 Nov 8.

Abstract

OBJECTIVES

Childhood obesity has become a global threat due to its serious negative consequences. We aimed to determine the patterns of metabolic syndrome and cardio-metabolic risk factors in Turkish children with obesity.

METHODS

We examined 169 schoolchildren with obesity in April and May 2019 in Samsun, Turkey. After clinical evaluation and anthropometric measurements, fasting blood samples were collected to measure total cholesterol, low and high-density lipoprotein, fasting blood glucose, triglycerides, and insulin levels.

RESULTS

The proportion of those who met the metabolic syndrome criteria in boys was 14.3%, but it was twice as high in girls (28.2%). The most prevalent component of cardio-metabolic risk factor was increased waist circumference (96.4%) followed by a high homeostasis model assessment insulin resistance index (74.6%) and high blood pressure (29.0%). While the average high-density lipoprotein was higher in boys than in girls, on the contrary, insulin, HbA1c, and homeostasis model assessment insulin resistance concentrations were higher in girls. The prevalence of dyslipidemia was also higher in girls (67.1%) than in boys (47.6%), as were all impaired metabolic syndrome components.

CONCLUSIONS

One in five children with obesity was at risk of metabolic syndrome. For early intervention and prevention, children with obesity should be monitored in terms of cardio-metabolic risk factors, but obese girls are more prioritized.

摘要

目的

由于其严重的负面影响,儿童肥胖已成为全球性威胁。本研究旨在确定土耳其肥胖儿童代谢综合征和心血管代谢危险因素的模式。

方法

我们于 2019 年 4 月至 5 月在土耳其萨姆松检查了 169 名肥胖学童。在临床评估和人体测量学测量后,采集空腹血样以测量总胆固醇、低和高密度脂蛋白、空腹血糖、甘油三酯和胰岛素水平。

结果

男孩中符合代谢综合征标准的比例为 14.3%,但女孩的比例是男孩的两倍(28.2%)。心血管代谢危险因素中最常见的是腰围增大(96.4%),其次是高稳态模型评估胰岛素抵抗指数(74.6%)和高血压(29.0%)。虽然男孩的平均高密度脂蛋白高于女孩,但相反,女孩的胰岛素、HbA1c 和稳态模型评估胰岛素抵抗浓度更高。女孩的血脂异常患病率(67.1%)也高于男孩(47.6%),所有代谢综合征受损成分的患病率也是如此。

结论

五分之一的肥胖儿童有代谢综合征风险。为了进行早期干预和预防,应监测肥胖儿童的心血管代谢危险因素,但肥胖女孩应优先考虑。

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