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在骨科肿瘤环境中Mako机器人手臂辅助全髋关节和全膝关节置换术的结果:病例系列

Mako robotic-arm-assisted total hip and total knee arthroplasty outcomes in an orthopedic oncology setting: A case series.

作者信息

Hoskins Tyler, Begley Brian, Giacalone Joseph D, De Wilde Kristen, Maguire Francis, Wittig James

机构信息

Weill Cornell Medical College, New York, NY, USA.

Cooper Medical School of Rowan University, Camden, NJ, USA.

出版信息

J Orthop. 2023 Oct 26;46:70-77. doi: 10.1016/j.jor.2023.10.021. eCollection 2023 Dec.

Abstract

BACKGROUND

The MAKO Robotic-Arm system is a cutting-edge technology which combines both computed tomography (CT) scanning and three-dimensional planning to determine the ideal size and orientation of implants prior to bone resection. It is typically utilized within a general orthopedic setting for joint replacement procedures, such as total joint arthroplasties. However, its use within orthopedic oncology, which contains a much more compromised patient population and more complex surgical treatment, is not well documented within the literature.

QUESTION/PURPOSES: To determine the patient outcomes of those who underwent a total hip arthroplasty (THA) or total knee arthroplasty (TKA) at Morristown Medical Center using the MAKO Robotic-Arm System. Particularly, we aspired to delve into the use of the MAKO in an orthopedic oncology setting for patients with a degenerative hip or knee and a history of cancer or other orthopedic tumor, impending pathological fracture, PVNS, chondromatosis, radiation therapy, or other oncological related conditions.

PATIENTS AND METHODS

Our institution monitored twenty-five individuals with unique orthopedic oncology conditions that underwent MAKO robotic-assisted total hip and knee arthroplasty. This was performed between 2020 and 2022 at Morristown Medical Center in New Jersey. During this time period, 52% (13/25) of the operations were performed on knees and 48% (12/25) were performed on hips. Data regarding patient demographics, body mass index (BMI), medications, hemoglobin, hematocrit, comorbidities, American Society of Anesthesiologists (ASA) Class, operative data, the length of stay (LOS), readmission rates due to infection or periprosthetic fractures, and complications were collected retrospectively. All confidence intervals were calculated at the 95% confidence level.

RESULTS

Postoperatively, the average LOS was 3.2 days, and there were no complications after any of the MAKO-assisted joint arthroplasty procedures. Additionally, there were no readmissions at any of our recorded intervals - 1-30, 1-60, 1-90, and 1 year - however one patient presented to the emergency department after falling 4 days post-operatively. X-ray imaging ultimately revealed no periprosthetic fracture or malalignment of the prosthesis.

CONCLUSIONS

The utilization of the MAKO Robotic-Arm System for joint arthroplasty procedures (THAs and TKAs) on orthopedic oncology patients yielded exceptional outcomes, with no complications or readmissions directly attributed to the use of this innovative robotic technology. Thus, this newly emerging surgical system holds great promise, potentially revolutionizing the approach for selected orthopedic oncology patients undergoing total joint arthroplasty compared to the traditional manual techniques. It further demonstrates that its use in an orthopedic oncology setting - where the cohort of patients are often compromised, leading to more intricate surgeries with heightened risks - elicits safety and provides optimal outcomes for patients. Nevertheless, its role within the field is evolving, and in the coming years, as it gains further popularity and sees broader application by orthopedic oncology surgeons, its potential will become clearer. To solidify its position, future clinical investigations and prospective research should be conducted to support the preference of the MAKO system over traditional manual techniques. This will help provide the necessary evidence to advocate for its widespread adoption and continued advancements in orthopedic oncology procedures.

摘要

背景

MAKO机器人手臂系统是一项前沿技术,它结合了计算机断层扫描(CT)和三维规划,以便在骨切除术前确定植入物的理想尺寸和方向。它通常用于普通骨科环境中的关节置换手术,如全关节置换术。然而,在骨科肿瘤学领域,其患者群体情况更复杂,手术治疗也更复杂,该技术在文献中的记载并不充分。

问题/目的:确定在莫里斯敦医疗中心使用MAKO机器人手臂系统进行全髋关节置换术(THA)或全膝关节置换术(TKA)的患者的治疗结果。特别是,我们希望深入研究MAKO在骨科肿瘤学环境中对患有退行性髋关节或膝关节疾病且有癌症或其他骨科肿瘤病史、即将发生病理性骨折、色素沉着绒毛结节性滑膜炎(PVNS)、滑膜软骨瘤病、放射治疗或其他肿瘤相关疾病的患者的应用情况。

患者和方法

我们的机构对25名患有独特骨科肿瘤疾病并接受MAKO机器人辅助全髋关节和膝关节置换术的患者进行了监测。手术于2020年至2022年在新泽西州的莫里斯敦医疗中心进行。在此期间,52%(13/25)的手术在膝关节进行,48%(12/25)的手术在髋关节进行。回顾性收集了患者人口统计学数据、体重指数(BMI)、用药情况、血红蛋白、血细胞比容、合并症、美国麻醉医师协会(ASA)分级、手术数据、住院时间(LOS)、因感染或假体周围骨折导致的再入院率以及并发症等信息。所有置信区间均在95%置信水平下计算。

结果

术后,平均住院时间为3.2天,在任何MAKO辅助关节置换手术之后均未出现并发症。此外,在我们记录的任何时间段——1 - 30天、1 - 60天、1 - 90天和1年——均无再入院情况,不过有1名患者在术后4天摔倒后前往急诊科就诊。X线成像最终显示无假体周围骨折或假体排列不齐。

结论

MAKO机器人手臂系统用于骨科肿瘤患者的关节置换手术(THA和TKA)取得了优异的结果,没有直接归因于使用这种创新机器人技术的并发症或再入院情况。因此,这种新兴的手术系统前景广阔,与传统手动技术相比,有可能彻底改变部分骨科肿瘤患者接受全关节置换术的方式。这进一步表明,在骨科肿瘤学环境中使用该系统——该环境中的患者群体往往情况不佳,导致手术更复杂、风险更高——对患者来说是安全的,并能提供最佳结果。然而,它在该领域的作用仍在不断发展,在未来几年,随着它越来越受欢迎并被骨科肿瘤外科医生更广泛地应用,其潜力将变得更加清晰。为巩固其地位,应开展未来的临床研究和前瞻性研究,以支持MAKO系统优于传统手动技术的观点。这将有助于提供必要的证据,以倡导其在骨科肿瘤手术中广泛应用并持续发展。

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