Zhou Jin, Wang Wei
Medical Oncology Department of Gastrointestinal Tumors, Liaoning Cancer Hospital & Institute, Cancer Hospital of Dalian University of Technology, Shenyang, Liaoning, China.
Department of Thoracic Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang, Liaoning, China.
Int Wound J. 2023 Nov 10;21(2). doi: 10.1111/iwj.14455.
It is still a matter of debate whether the surgical segmentectomy and lobectomy of lung cancer are comparable in the incidence of perioperative wound complications. An extensive review of the literature through August 2023 was carried out with a critical review of four databases. Following the acceptance and elimination criteria set out in the trial, as well as a qualitative assessment of the literature, this resulted in a review of related research that compared the results of both lobectomy and partial resection in the management of lung cancer. The analysis of the data was performed with the RevMan 5.3 software, and the 95% confidence interval [CI] and odds ratio [OR] were performed with either stationary or random-effect models. It is concluded that the operation time of lobectomy is shorter than that of sectioning in the treatment of segmentectomy (mean difference [MD], -38.62; 95% CI, -41.96, -35.28; p < 0.0001). But the rate of postoperative wound infection (OR, 0.62; 95% CI, 0.18, 2.15; p = 0.45) and intraoperative blood loss (MD, 17.54; 95% CI, -4.19, 39.26; p = 0.11) were not significantly different for them. Thus, for those who have received a pulmonary carcinoma operation, different operative methods might not have an impact on the incidence of postoperative wound infections. The operative procedure appears to have a major impact on the length of the operation in patients.
肺癌的手术肺段切除术和肺叶切除术在围手术期伤口并发症发生率方面是否具有可比性仍是一个有争议的问题。通过对四个数据库进行严格审查，对截至2023年8月的文献进行了广泛回顾。按照试验中设定的纳入和排除标准，以及对文献的定性评估，最终对比较肺叶切除术和部分切除术在肺癌治疗中结果的相关研究进行了综述。使用RevMan 5.3软件进行数据分析，并采用固定效应模型或随机效应模型计算95%置信区间[CI]和比值比[OR]。结果表明，在治疗肺段切除术中，肺叶切除术的手术时间比肺段切除术短（平均差值[MD]，-38.62；95% CI，-41.96，-35.28；p < 0.0001）。但两者术后伤口感染率（OR，0.62；95% CI，0.18，2.15；p = 0.45）和术中失血量（MD，17.54；95% CI，-4.19，39.26；p = 0.11）无显著差异。因此，对于接受肺癌手术的患者，不同的手术方式可能对术后伤口感染发生率没有影响。手术操作似乎对患者的手术时长有重大影响。
