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病例系列:血管畸形手术治疗中的术中神经监测与血管造影

Case series: Intraoperative neuromonitoring and angiography in the surgical treatment of vascular malformations.

作者信息

Šmigoc Tomaž, Kozorog Ninna, Ravnik Janez

机构信息

Department of Neurosurgery, Surgical Clinic, UMC Maribor, Maribor, Slovenia.

出版信息

Front Neurol. 2023 Oct 26;14:1182576. doi: 10.3389/fneur.2023.1182576. eCollection 2023.

Abstract

In the surgical treatment of cerebral vascular malformations, e.g., aneurysms and arteriovenous malformations, the risk of ischemic complications is 6.7%, and a residual aneurysm is possible in 5.2% of these cases. Ischemic lesions can result in permanent neurological deficits, and a residual aneurysm can lead to the recurrence of the aneurysm in 2% of cases. In this article, we present five cases (two cases of ruptured aneurysms, two cases of non-ruptured aneurysms, and a case of arteriovenous malformation) in which we reduced the aforementioned risks with the use of intraoperative neuromonitoring and angiography. Intraoperative neuromonitoring (IONM) is used to measure motor and sensory-evoked potentials to detect brain hypoperfusion. Intraoperative angiography with the dye indocyanine green (ICG-A), which fluoresces in a vessel under a microscope after intravenous administration, helps to identify residual aneurysm sacs and distal blood flow. With the use of IONM and ICG-A, we identified abnormalities and adjusted our interventions and treatments. IONM and ICG-A can lead to a better outcome after surgical treatment of cerebral vascular abnormalities.

摘要

在脑血管畸形(如动脉瘤和动静脉畸形)的外科治疗中,缺血性并发症的风险为6.7%,其中5.2%的病例可能残留动脉瘤。缺血性病变可导致永久性神经功能缺损,残留动脉瘤在2%的病例中可导致动脉瘤复发。在本文中,我们介绍了5例(2例破裂动脉瘤、2例未破裂动脉瘤和1例动静脉畸形)通过术中神经监测和血管造影降低上述风险的病例。术中神经监测(IONM)用于测量运动和感觉诱发电位以检测脑灌注不足。术中使用静脉注射后在显微镜下血管中发出荧光的吲哚菁绿(ICG-A)进行血管造影,有助于识别残留的动脉瘤囊和远端血流。通过使用IONM和ICG-A,我们识别出异常情况并调整了干预措施和治疗方法。IONM和ICG-A可使脑血管异常的外科治疗取得更好的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68d6/10637549/b43afa4e8235/fneur-14-1182576-g001.jpg

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