左右看看：临床研究中的审查。
Look left, look right: censoring in clinical research.
机构信息
Department of Clinical Epidemiology, Leiden University Medical Center, Albinusdreef 2, Leiden 2333 ZA, The Netherlands.
Department of Biomedical Data Sciences, Leiden University Medical Center, Albinusdreef 2, Leiden 2333 ZA, The Netherlands.
出版信息
Eur J Endocrinol. 2023 Nov 8;189(5):E1-E3. doi: 10.1093/ejendo/lvad152.
In this methodology editorial, the problem of censored survival (or time-to-event) data in clinical research is discussed. In case of censored observations, part of the observation time for some participants in a study is unobserved, which means that measures such as an average survival time cannot be calculated. Instead, censored survival time should explicitly be accounted for in the analysis of a study, for example using the Kaplan-Meier method. Implications of censoring and how to deal with it in the analysis of a study or when reading a research paper are discussed.
在本方法学社论中，讨论了临床研究中删失生存（或事件时间）数据的问题。在存在删失观测的情况下，研究中某些参与者的部分观测时间未被观测到，这意味着无法计算平均生存时间等指标。相反，应该在研究分析中明确考虑删失生存时间，例如使用 Kaplan-Meier 方法。本文讨论了删失的影响以及在研究分析中或阅读研究论文时如何处理删失。
Zotero 插件