Department of Surgery, SCB Medical College and Hospital, Cuttack, India.
Department of Surgery, SCB Medical College and Hospital, Cuttack, India.
Indian J Tuberc. 2023 Oct;70(4):422-429. doi: 10.1016/j.ijtb.2023.01.002. Epub 2023 Jan 14.
Abdominal tuberculosis presenting as acute surgical emergency continues to be a major issue in developing countries including India. Being an indolent disease with varied presentation, there is a need to describe the epidemiology, clinicopathological nature of the disease. Hence, this series was conducted with the aim of describing our institutional experience in the management of abdominal tuberculosis presenting as acute surgical emergency, outlining the epidemiology, management aspects and the analysis of risk factors for poor outcome in our population.
This was a descriptive series of patients operated for abdominal tuberculosis presenting as acute surgical emergency at a tertiary care hospital in Eastern India from January 2021 to January 2022. All consecutive patients presenting with intestinal obstruction or peritonitis who underwent laparotomy with intra operative and histopathological finding suggestive of tuberculosis were taken for the study.
A total of 30 patients with acute abdominal tuberculosis were included in the study. 56.7% of patients were males; the mean age of presentation was 43 years with majority of patients in the younger to middle age groups. Most (80%) patients were from rural areas with limited access to healthcare. One patient had co-infection with HIV. Five patients had diabetes and six patients had hypertension as co-morbidities. 73.3% of patients had primary intestinal tuberculosis. Majority (76.7%) presented with acute intestinal obstruction. All patients had colicky abdominal pain as a consistent feature. 40% of patients were anaemic and 70% had low serum albumin levels. The most common site of affection was Ileo-cecal region (73.3%) with stricture as the pathology. Segmental resection with end to end anastomosis was the most common procedure performed (46.7%). 26.7% of patients had an adverse post operative complication, and 23.3% had surgical site infection (SSI). The mortality rate in our series was 6.7%. Although coexisting SSI, co-morbidities were associated with increased mortality, it was not found to be statistically significant (p = 0.08). 16 patients were lost to follow up.
Abdominal tuberculosis presenting as acute abdomen continues to challenge surgeons even in the 21st century. Majority in the developing countries present late with varied complications. A high index of clinical suspicion is required for timely diagnosis to reduce the mortality and morbidity of the disease.
在包括印度在内的发展中国家,以急性外科急症形式出现的腹部结核仍然是一个主要问题。由于该病具有惰性和多种表现形式,因此需要描述其流行病学和临床病理性质。因此,本系列旨在描述我们在管理以急性外科急症形式出现的腹部结核方面的机构经验,概述我们人群中不良结局的流行病学、管理方面和危险因素分析。
这是一项描述性系列研究,纳入了 2021 年 1 月至 2022 年 1 月在印度东部一家三级保健医院因急性外科急症接受手术治疗的腹部结核患者。所有接受剖腹手术的肠梗 阻或腹膜炎患者,术中发现和组织病理学检查提示结核病,均纳入本研究。
共有 30 例急性腹部结核患者纳入本研究。56.7%的患者为男性;发病时的平均年龄为 43 岁,大多数患者处于年轻到中年年龄段。大多数(80%)患者来自农村地区,获得医疗保健的机会有限。1 例患者合并感染 HIV。5 例患者患有糖尿病,6 例患者患有高血压作为合并症。73.3%的患者有原发性肠结核。大多数(76.7%)患者以急性肠梗阻为首发症状。所有患者均有阵发性腹痛,这是一个一致的特征。40%的患者贫血,70%的患者血清白蛋白水平较低。最常见的受累部位是回盲部(73.3%),以狭窄为主要病理改变。最常见的手术方式是节段性切除加端端吻合术(46.7%)。26.7%的患者术后出现不良并发症,23.3%的患者发生手术部位感染(SSI)。本系列的死亡率为 6.7%。尽管合并 SSI 和合并症与死亡率增加相关,但无统计学意义(p=0.08)。16 例患者失访。
即使在 21 世纪,以急性腹痛为表现的腹部结核仍然对外科医生构成挑战。发展中国家的大多数患者就诊较晚,伴有多种并发症。需要高度的临床怀疑指数来进行及时诊断,以降低疾病的死亡率和发病率。