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建立膝关节内侧单髁关节成形术后膝关节损伤和骨关节炎结局评分的以患者为中心的指标。

Establishing patient-centered metrics for the knee injury and osteoarthritis outcome score following medial unicompartmental knee arthropalsty.

机构信息

Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH, USA.

出版信息

Knee. 2024 Jan;46:1-7. doi: 10.1016/j.knee.2023.10.013. Epub 2023 Nov 14.

Abstract

BACKGROUND

This study aimed to determine the minimal clinically important difference (MCID) and the patient acceptable symptoms state (PASS) threshold for the knee injury and osteoarthritis outcome score (KOOS) pain subscore, KOOS physical short form (PS), and KOOS joint replacement (JR) following medial unicompartmental knee arthroplasty (mUKA).

METHODS

Prospectively collected data from 743 patients undergoing mUKA from a single academic institution from April 2015 through March 2020 were analyzed. Patient-reported outcome measures (PROMs) were collected both pre-operatively and 1-year post-operatively. Distribution-based and anchored-based approaches were used to estimate MCIDs and PASS, respectively. The optimal cut-off point and the percentage of patients who achieved PASS were also calculated.

RESULTS

MCID for KOOS-pain, KOOS-PS, and KOOS-JR following mUKA were calculated to be 7.6, 7.3, and 6.2, respectively. The PASS threshold for KOOS pain, PS, and JR were 77.8, 70.3, and 70.7, with 68%, 66%, and 64% of patients achieving satisfactory outcomes, respectively. Cut-off values for delta KOOS pain, PS, and JR were found to be 25.7, 14.3, and 20.7 with 73%, 69%, and 68% of patients achieving satisfactory outcomes, respectively.

CONCLUSION

The current study identified useful values for the MCID and PASS thresholds at 1 year following medial UKA of KOOS pain, KOOS PS, and KOOS JR scores. These values may be used as targets for surgeons when evaluating PROMS using KOOS to determine whether patients have achieved successful outcomes after their surgical intervention. Potential uses include the integration of these values into predictive models to enhance shared decision-making and guide more informed decisions to optimize patient outcomes.

LEVEL OF EVIDENCE

III.

摘要

背景

本研究旨在确定内侧单髁膝关节置换术(mUKA)后膝关节损伤和骨关节炎结局评分(KOOS)疼痛子评分、KOOS 简易量表(PS)和 KOOS 关节置换(JR)的最小临床重要差异(MCID)和患者可接受症状状态(PASS)阈值。

方法

对 2015 年 4 月至 2020 年 3 月期间,来自单一学术机构的 743 例接受 mUKA 的患者前瞻性收集数据。在术前和术后 1 年收集患者报告的结局测量(PROM)。分别使用基于分布和基于锚定的方法来估计 MCID 和 PASS。还计算了最佳截止值和达到 PASS 的患者比例。

结果

mUKA 后 KOOS 疼痛、KOOS PS 和 KOOS JR 的 MCID 分别计算为 7.6、7.3 和 6.2。KOOS 疼痛、PS 和 JR 的 PASS 阈值分别为 77.8、70.3 和 70.7,分别有 68%、66%和 64%的患者达到了满意的结局。Delta KOOS 疼痛、PS 和 JR 的截止值分别为 25.7、14.3 和 20.7,分别有 73%、69%和 68%的患者达到了满意的结局。

结论

本研究确定了 mUKA 后 1 年 KOOS 疼痛、KOOS PS 和 KOOS JR 评分的 MCID 和 PASS 阈值的有用值。这些值可作为外科医生使用 KOOS 评估 PROMS 时确定患者是否在手术干预后取得成功结局的目标。潜在用途包括将这些值纳入预测模型,以增强共同决策并指导更明智的决策,以优化患者结局。

证据水平

III 级。

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