Section of Endocrine Surgery, Yale New Haven Hospital, New Haven, CT. Electronic address: https://twitter.com/NikitaMachado.
Medical Scientist Training Program, Yale University School of Medicine, New Haven, CT.
Surgery. 2024 Jan;175(1):114-120. doi: 10.1016/j.surg.2023.06.052. Epub 2023 Nov 15.
Enhanced recovery after surgery pathways have become the standard of care in various surgical specialties. In this study, we discuss our initial experience with a staged enhanced recovery after surgery pathway in endocrine surgery and assess the impact of this pathway on select perioperative outcomes and unanticipated admissions.
We collected information regarding all thyroid/parathyroid surgeries performed by endocrine surgeons at our institution before and after the implementation of the multi-intervention enhanced recovery after surgery pathway. We compared relevant outcomes for all cases 1 year before (n = 479) and 1 year after (n = 166) implementation of the pathway. We also compared outcomes between enhanced recovery after surgery patient groups with varying levels of enhanced recovery after surgery compliance.
Enhanced recovery after surgery was associated with a significant decrease in total length of stay (9.2 vs 7.5 hours, P < .0001). Whereas there was no significant decrease in all-cause unanticipated postoperative admissions, there was a decrease in patient-initiated admissions in the Enhanced recovery after surgery group. There was also a significant decrease in mean postoperative morphine milligram equivalents (14.4 vs 16.2 vs 24.8, P = .0015), average daily morphine milligram equivalents (25.6 vs 45.6 vs 53, P < .0001), and average daily pain scores (1.89 vs 2.38 vs 2.74, P = .0045) in the Enhanced recovery after surgery group (particularly with increasing Enhanced recovery after surgery compliance). There were no significant differences in the requirement for postoperative antiemetics or in the post-anesthesia care unit length of stay.
This study demonstrates a significant benefit from Enhanced recovery after surgery pathways for thyroidectomies and parathyroidectomies, even with initial data and a staggered roll-out plan. Further directions include a follow-up study once we reach a higher level of institutional compliance with all components of the Enhanced Recovery After Surgery pathway and a prospective trial to identify the relative significance of different portions of the Enhanced Recovery after Surgery pathway, particularly the superficial cervical plexus block.
手术后恢复加速方案已成为多个外科专业的标准治疗方法。在本研究中,我们讨论了在我们的内分泌外科中实施分阶段手术后恢复加速方案的初步经验,并评估了该方案对特定围手术期结果和意外住院的影响。
我们收集了在我们的机构进行的所有甲状腺/甲状旁腺手术的信息,这些手术是在实施多干预手术后恢复加速方案之前(n=479)和之后(n=166)进行的。我们比较了方案实施前后所有病例的相关结果。我们还比较了不同程度的手术后恢复加速方案依从性的手术后恢复加速方案患者组之间的结果。
手术后恢复加速方案与总住院时间的显著减少相关(9.2 小时对 7.5 小时,P<0.0001)。虽然所有原因的意外术后住院人数没有显著减少,但在手术后恢复加速方案组中,患者发起的住院人数有所减少。术后吗啡毫克当量的平均用量(14.4 对 16.2 对 24.8,P=0.0015)、平均每日吗啡毫克当量(25.6 对 45.6 对 53,P<0.0001)和平均每日疼痛评分(1.89 对 2.38 对 2.74,P=0.0045)也显著降低,尤其是在手术后恢复加速方案依从性增加的情况下。术后止吐药的需求和麻醉后护理单元的住院时间没有显著差异。
即使有初步数据和分阶段推出计划,本研究也表明甲状腺切除术和甲状旁腺切除术的手术后恢复加速方案有显著的益处。进一步的方向包括在我们达到更高水平的机构对手术后恢复加速方案的所有组成部分的依从性后进行后续研究,以及进行前瞻性试验以确定手术后恢复加速方案不同部分的相对重要性,特别是浅表颈丛阻滞。