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是时候让腹膜透析在急性肾损伤管理中发挥应有的作用了:从 COVID-19 大流行中吸取的教训。

Is It Time to Give Peritoneal Dialysis Its Due Place in Managing Acute Kidney Injury: Lessons Learnt from COVID-19 Pandemic.

机构信息

Monash Rural Health Mildura, Monash University, Melbourne, Victoria, Australia.

Department of Renal Medicine, Woodlands Health, Singapore, Singapore.

出版信息

Blood Purif. 2024;53(2):71-79. doi: 10.1159/000535243. Epub 2023 Nov 17.

Abstract

Despite comparable outcomes with the extracorporeal dialysis modalities, peritoneal dialysis (PD) is seldom considered a viable option for managing acute kidney injury (AKI) in developed and resource-rich countries, where continuous renal replacement therapies (CRRTs) are the mainstay of treating AKI. PD has fewer infrastructure requirements and has been shown to save lives during conflicts, natural disasters, and pandemics. During the ongoing COVID-19 pandemic, the developed world was confronted with a sudden surge in critically ill AKI patients requiring renal replacement therapy. There were acute shortages of CRRT machines and the trained staff to deliver those treatments. Some centres developed acute PD programmes to circumvent these issues with good results. This experience re-emphasised the suitability of PD for managing AKI. It also highlighted the need to review the current management strategies for AKI in developed countries and consider incorporating PD as a viable tool for suitable patients. This article reviews the current evidence of using PD in AKI, attempts to clarify some misconceptions about PD in AKI, and argues in favour of developing acute PD programmes.

摘要

尽管与体外透析模式相比具有可比的结果,但腹膜透析(PD)在发达国家和资源丰富的国家很少被认为是治疗急性肾损伤(AKI)的可行选择,在这些国家,连续肾脏替代疗法(CRRT)是治疗 AKI 的主要方法。PD 的基础设施要求较少,并且已被证明在冲突、自然灾害和大流行期间可以挽救生命。在持续的 COVID-19 大流行期间,发达国家突然面临大量需要肾脏替代治疗的重症 AKI 患者。CRRT 机和提供这些治疗的训练有素的工作人员严重短缺。一些中心制定了急性 PD 计划来解决这些问题,并取得了良好的效果。这一经验再次强调了 PD 适合管理 AKI。它还强调了有必要审查发达国家 AKI 的现行管理策略,并考虑将 PD 作为适合患者的可行工具。本文回顾了 PD 在 AKI 中的应用的现有证据,试图澄清 AKI 中 PD 的一些误解,并支持制定急性 PD 计划。

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本文引用的文献

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