Soletti Giovanni Jr, Dell'Aquila Michele, Harik Lamia, Cancelli Gianmarco, Alzghari Talal, Perezgrovas-Olaria Roberto, Dimagli Arnaldo, An Kevin R, Leith Jordan, Rossi Camilla Sofia, Barile Christopher F, Demetres Michelle, Lau Christopher, Girardi Leonard N, Gaudino Mario
Department of Cardiothoracic Surgery, Weill Cornell Medicine, 525 East 68th Street, New York, NY 10021, USA.
Samuel J. Wood Library and C.V. Starr Biomedical Information Centre, Weill Cornell Medicine, New York, NY 10021, USA.
J Cardiovasc Dev Dis. 2023 Nov 7;10(11):453. doi: 10.3390/jcdd10110453.
Saphenous vein grafts (SVGs) are the most frequently used conduits in coronary artery bypass grafting (CABG), but their higher rate of occlusion compared to arterial conduits remains a concern. Previous studies have shown that SVG failure is mainly driven by intimal hyperplasia, an adaptative response to higher pressures of the arterial circulation. The VEST device (Vascular Graft Solutions, Tel Aviv, Israel), an external support designed to mitigate intimal hyperplasia in SVGs, has been tested in few clinical trials (RCTs). Herein, we descriptively evaluated the randomized evidence on the VEST device.
大隐静脉移植物（SVG）是冠状动脉旁路移植术（CABG）中最常用的血管移植物，但与动脉血管移植物相比，其较高的闭塞率仍是一个问题。先前的研究表明，SVG失败主要是由内膜增生驱动的，内膜增生是对动脉循环较高压力的一种适应性反应。VEST装置（Vascular Graft Solutions，以色列特拉维夫）是一种旨在减轻SVG内膜增生的外部支撑装置，仅在少数临床试验（随机对照试验）中进行了测试。在此，我们对VEST装置的随机证据进行了描述性评估。
