Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Xinquan Road 29#, Fuzhou, 350001, P. R. China.
Key Laboratory of Cardio-Thoracic Surgery, Fujian Medical University, Fujian Province University, Fuzhou, 350001, P. R. China.
BMC Cardiovasc Disord. 2023 Nov 24;23(1):580. doi: 10.1186/s12872-023-03617-w.
To compare the post-operative pain and quality of life of patients who underwent total thoracoscopic surgery (TTS) or conventional full-sternotomy (CFS) for aortic valve replacement (AVR).
We reviewed the records of 223 consecutive AVR patients with either TTS or CFS from January 2018 to December 2022. We used a visual analogue scale (VAS) and the Short Form-36 Health Survey (SF-36) to measure the post-operative pain and quality of life, respectively. We also compared the operative data and clinical outcomes between the two groups.
The TTS group had lower adjusted mean VAS scores than the CFS group at all time points after surgery (at 1 to 3 days and at 3 and 6 months, p < .001 for all comparisons), indicating less pain. The TTS group also had higher mean SF-36 scores than the CFS group up to 6 months after surgery (p < .001 for all comparisons), indicating better quality of life. The operative time was similar between the two groups (p = .224), but the TTS group had longer cardiopulmonary bypass time and aortic cross-clamp time than the CFS group (p < .001). The TTS group had more pulmonary complications than the CFS group (p = .023). However, there were no significant differences in other major complications or mortality between the two groups.
TTS is a safe and effective alternative to CFS for AVR. TTS resulted in less pain and better quality of life, especially in the early recovery period. However, further prospective randomized controlled studies are needed to confirm our findings.
比较全胸腔镜手术(TTS)与传统胸骨正中切开术(CFS)治疗主动脉瓣置换术(AVR)的术后疼痛和生活质量。
回顾了 2018 年 1 月至 2022 年 12 月期间 223 例接受 TTS 或 CFS 的 AVR 患者的连续记录。分别采用视觉模拟评分(VAS)和简明健康调查问卷(SF-36)来测量术后疼痛和生活质量。比较了两组的手术数据和临床结果。
TTS 组术后所有时间点的调整后 VAS 评分均低于 CFS 组(术后 1-3 天和术后 3、6 个月,所有比较均 p<0.001),表明疼痛较轻。TTS 组术后 6 个月时的 SF-36 评分也高于 CFS 组(所有比较均 p<0.001),表明生活质量较好。两组的手术时间相似(p=0.224),但 TTS 组的体外循环时间和主动脉阻断时间长于 CFS 组(均 p<0.001)。TTS 组的肺部并发症多于 CFS 组(p=0.023)。但两组间其他主要并发症或死亡率无显著差异。
TTS 是 AVR 的一种安全有效的 CFS 替代方法。TTS 可减轻疼痛,提高生活质量,尤其是在早期康复期。但仍需要前瞻性随机对照研究来证实我们的发现。