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急性出现的大型前庭神经鞘瘤的两阶段手术治疗:两例报告。

Two-Stage Surgical Management for Acutely Presented Large Vestibular Schwannomas: Report of Two Cases.

作者信息

Keles Abdullah, Ozaydin Burak, Erginoglu Ufuk, Baskaya Mustafa K

机构信息

Department of Neurological Surgery, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI 53792, USA.

出版信息

Brain Sci. 2023 Nov 4;13(11):1548. doi: 10.3390/brainsci13111548.

Abstract

The surgical management of vestibular schwannomas should be based on their presentation, neuro-imaging findings, surgeons' expertise, and logistics. Multi-stage surgery can be beneficial for large-sized lesions with acute presentations. Herein, we highlighted the indications for two cases managed initially through the retrosigmoid and, subsequently, translabyrinthine approaches. The first case presented with acute balance and gait issues and a long history of hearing loss and blurred vision. Neuroimaging findings revealed a cerebellopontine angle lesion, resembling a vestibular schwannoma, with significant brainstem compression and hydrocephalus. Due to the rapidly deteriorating clinical status and large-sized tumor, we first proceeded with urgent decompression via a retrosigmoid approach, followed by gross total resection via a translabyrinthine approach two weeks later. The second case presented with gradually worsening dizziness and hemifacial numbness accompanied by acute onset severe headaches and hearing loss. Neuroimaging findings showed a large cerebellopontine angle lesion suggestive of a vestibular schwannoma with acute intratumoral hemorrhage. Given the acute clinical deterioration and large size of the tumor, we performed urgent decompression with a retrosigmoid approach followed by gross total resection through a translabyrinthine approach a week later. Post-surgery, both patients showed excellent recovery. When managing acutely presented large-sized vestibular schwannomas, immediate surgical decompression is vital to avoid permanent neurological deficits.

摘要

前庭神经鞘瘤的外科治疗应基于其临床表现、神经影像学检查结果、外科医生的专业技能以及后勤保障。对于具有急性临床表现的大型病变,多阶段手术可能有益。在此,我们重点介绍了两例最初通过乙状窦后入路、随后通过迷路后入路进行治疗的病例。第一例患者出现急性平衡和步态问题,并有长期听力丧失和视力模糊病史。神经影像学检查结果显示桥小脑角病变,类似前庭神经鞘瘤,伴有明显脑干受压和脑积水。由于临床状况迅速恶化且肿瘤较大,我们首先通过乙状窦后入路进行紧急减压,两周后通过迷路后入路进行肿瘤全切。第二例患者出现逐渐加重的头晕和半侧面部麻木,并伴有急性发作的严重头痛和听力丧失。神经影像学检查结果显示桥小脑角有一个大病变,提示为伴有急性瘤内出血的前庭神经鞘瘤。鉴于临床急性恶化和肿瘤较大,我们采用乙状窦后入路进行紧急减压,一周后通过迷路后入路进行肿瘤全切。术后,两名患者均恢复良好。在处理急性出现的大型前庭神经鞘瘤时,立即进行手术减压对于避免永久性神经功能缺损至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8f3/10669422/cfd274bacece/brainsci-13-01548-g001.jpg

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