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退行性腰椎侧弯患者步态特征的套索分析及其与脊柱骨盆参数的相关性

Lasso Analysis of Gait Characteristics and Correlation with Spinopelvic Parameters in Patients with Degenerative Lumbar Scoliosis.

作者信息

Guo Chen, Liang Yan, Xu Shuai, Zheng Bin, Liu Haiying

机构信息

Department of Spinal Surgery, Peking University People's Hospital, Peking University, Beijing 100044, China.

出版信息

J Pers Med. 2023 Nov 3;13(11):1576. doi: 10.3390/jpm13111576.

Abstract

PURPOSE

This study quantifies the gait characteristics of patients with degenerative lumbar scoliosis (DLS) and patients with simple lumbar spinal stenosis (LSS) by means of a three-dimensional gait analysis system, aiming to determine the image of spinal deformity on gait and the correlation between spinal-pelvic parameters and gait characteristics in patients with DLS to assist clinical work.

METHODS

From June 2020 to December 2021, a total of 50 subjects were enrolled in this study, of whom 20 patients with DLS served as the case group and 30 middle-aged and elderly patients with LSS were selected as the control group according to the general conditions (sex, age, and BMI) of the case group. Spinal-pelvic parameters were measured by full-length frontal and lateral spine films one week before surgery, and kinematics were recorded on the same day using a gait analysis system.

RESULTS

Compared to the control group, DLS patients exhibited significantly reduced velocity and cadence; gait variability and symmetry of both lower limbs were notably better in the LSS group than in the DLS group; joint ROM (range of motion) across multiple dimensions was also lower in the DLS group; and correlation analysis revealed that patients with a larger Cobb angle, T1PA, and higher CSVA tended to walk more slowly, and those with a larger PI, PT, and LL usually had smaller stride lengths. The greater the PI-SS mismatch, the longer the patient stayed in the support phase. Furthermore, a larger Cobb angle correlated with worse coronal hip mobility.

CONCLUSIONS

DLS patients demonstrate distinctive gait abnormalities and reduced hip mobility compared to LSS patients. Significant correlations between crucial spinopelvic parameters and these gait changes underline their potential influence on gait disturbances in DLS. Our study identifies a Cobb angle cut-off of 16.1 as a key predictor for gait abnormalities. These insights can guide personalized treatment and intervention strategies, ultimately improving the quality of life for DLS patients.

摘要

目的

本研究通过三维步态分析系统量化退变性腰椎侧凸(DLS)患者和单纯腰椎管狭窄症(LSS)患者的步态特征,旨在确定脊柱畸形在步态上的表现以及DLS患者脊柱 - 骨盆参数与步态特征之间的相关性,以辅助临床工作。

方法

2020年6月至2021年12月,本研究共纳入50名受试者,其中20例DLS患者作为病例组,根据病例组的一般情况(性别、年龄和BMI)选择30例中老年LSS患者作为对照组。术前一周通过全长脊柱正侧位片测量脊柱 - 骨盆参数,并于同日使用步态分析系统记录运动学数据。

结果

与对照组相比,DLS患者的速度和步频显著降低;LSS组双下肢的步态变异性和对称性明显优于DLS组;DLS组多个维度的关节活动度(ROM)也较低;相关性分析显示,Cobb角、T1PA较大且CSVA较高的患者往往行走较慢,而PI、PT较大且LL较高的患者步长通常较小。PI - SS不匹配越大,患者在支撑相停留的时间越长。此外,Cobb角越大,冠状面髋关节活动度越差。

结论

与LSS患者相比,DLS患者表现出独特的步态异常和髋关节活动度降低。关键的脊柱 - 骨盆参数与这些步态变化之间存在显著相关性,突显了它们对DLS步态障碍的潜在影响。我们的研究确定Cobb角截断值为16.1是步态异常的关键预测指标。这些见解可指导个性化治疗和干预策略,最终改善DLS患者的生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b86/10671873/9ba8be54d2ca/jpm-13-01576-g001.jpg

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